Activities per year
Abstract
Background. We aimed to estimate the trends in dispensing rate and the spectrum of all state-funded lipid-lowering medications (LLMs) in Latvia over a decade. Methods. Using data from the National Health Service of the Republic of Latvia, we retrospectively analyzed all dispensed LLM-containing drug units in a ten-year period from 2012 to 2021. Results. In Latvia, 318.2 million oral and 994 subcutaneous units of LLMs were dispensed over a decade. Statins were the most dispensed LLMs (94.5%), and their use doubled from 19.7 to 43.5 million units. The proportion of high-intensity statins increased from 31.3% to 45.2%. The dispensing rate of ezetimibe increased from 184.7 thousand to 4.8 million. The share of fixed-dose statin combinations with ezetimibe grew from 0.2% to 10.0% among all statins and from 22.2% to 90.9% among all ezetimibe units. Statin use for primary and secondary prevention increased from 7.0 to 19.9 million and from 12.8 to 23.6 million units, respectively. Conclusion. The dispensing rate of statins doubled, and the use of ezetimibe increased more than 25 times in Latvia over a decade. The proportion of high-intensity statins increased from one third to almost half of all statins. Fixed-dose statin combinations with ezetimibe became frequently used.
Original language | English |
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Article number | 6390 |
Journal | Journal of clinical medicine |
Volume | 12 |
Issue number | 19 |
DOIs | |
Publication status | Published - Oct 2023 |
Keywords*
- dyslipidemia
- ezetimibe
- fenofibrate
- fixed-dose combination
- lipid-lowering medications
- PCSK9 inhibitors
- statins
- trends
Field of Science*
- 3.1 Basic medicine
Publication Type*
- 1.1. Scientific article indexed in Web of Science and/or Scopus database
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- 1 Oral presentation
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Female patients with cardiovascular diseases are treated with lower statin doses when used in combination with ezetimibe in Latvia
Praškilēvics, A. (Speaker), Urtāne, I. (Co-author) & Latkovskis, G. (Co-author)
5 Apr 2024Activity: Talk or presentation types › Oral presentation