Neuropathic ulcers: a focused review

Brittany Urso, Mondana Ghias, Anan John, Amor Khachemoune (Coresponding Author)

Research output: Contribution to journalReview articlepeer-review

3 Citations (Scopus)


Neuropathic ulcers or diabetic foot ulcers are preventable ulcers associated with diabetes mellitus. These ulcers occur in the setting of unrecognized trauma, peripheral neuropathy, and foot deformities; however, they are often complicated by peripheral arterial disease and infection. Approximately 15% of individuals with a neuropathic ulcer require limb amputation as a result of infection. Not only are neuropathic ulcers a burden to the patient but also to the economy. The cost of diabetic foot ulcer care is approximately $1.38 billion per year. This makes neuropathic ulcers an important therapeutic target. This review presents the pathophysiology, clinical presentation, evaluation, management, and prevention of neuropathic ulcers.

Original languageEnglish
Pages (from-to)e383-e389
JournalInternational Journal of Dermatology
Issue number10
Publication statusPublished - Oct 2021
Externally publishedYes

Field of Science*

  • 3.2 Clinical medicine

Publication Type*

  • 1.1. Scientific article indexed in Web of Science and/or Scopus database


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