Opportunities of Amlodipine as a Potential Candidate in the Evaluation of Drug Compliance during Antihypertensive Therapy

Dmitrijs Kustovs (Corresponding Author), Inga Urtāne, Eduards Sevostjanovs, Eva Moreino, Kārlis Trušinskis

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)
17 Downloads (Pure)

Abstract

Background and Objectives: Blood pressure measurement is essential evidence to establish that the chosen medicine and dosage are appropriate, and also indirectly indicates whether the medicine is being used at all. Therefore, current research compares adherence to the target blood pressure at home and in the hospital between different age groups, using similar combinations of the drugs prescribed by the doctor within ongoing antihypertensive therapy. Moreover, it is very important to develop a method for the determination of amlodipine and its metabolite, which would suitable for clinical applications, when the result is needed as quick as possible. Materials and Methods: This prospective study included patients aged ≥18 years who were diagnosed with hypertension. Subjects were divided into two age groups according to European Society of Cardiology (ESC) hypertension guidelines; older patients (≥65 years) and adult patients (
Original languageEnglish
Article number340
JournalMedicina
Volume59
Issue number2
DOIs
Publication statusPublished - 10 Feb 2023

Keywords*

  • amlodipine
  • adherence
  • drug monitoring
  • dehydro-amlodipine
  • hypertension

Field of Science*

  • 3.2 Clinical medicine
  • 3.1 Basic medicine

Publication Type*

  • 1.1. Scientific article indexed in Web of Science and/or Scopus database

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