Optic nerve glioblastoma with optic chiasm involvement: A case report and a brief literature review

Artis Brokāns, Julija Dolgopolova, Agnis Saulitis, Uldis Spulle, Kristaps Rancans, Dairis Meiers, Sigita Hasnere, Arturs Balodis (Corresponding Author)

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Abstract

Abstract: Background: optic nerve glioblastoma is an uncommon pathology. The optic chiasm, optic
tract, or optic nerves are possible places from which the tumor can originate. Most of the neuroimag-
ing findings are nonspecific. To confirm the diagnosis, a biopsy is required. A delay to the treatment
plan for optic nerve glioblastoma results in poor patient survival rates. Case report: a 68-year-old
woman with an uncomplicated medical history presented with exophthalmos, deteriorating eyesight,
and partial loss of vision. Using radiological data together with postoperative histopathological
and histochemical analysis, optic nerve glioblastoma, IDH-wildtype, with optic chiasm involvement
was diagnosed. Conclusion: optic nerve glioblastoma is a rare and aggressive form of cancer that
affects the optic nerve, leading to significant vision impairment and potentially life-threatening
complications. Treatment options are restricted and difficult because of the location and nature
of the condition; surgery, radiation therapy, and chemotherapy are frequently needed as part of a
multidisciplinary approach
Original languageEnglish
Article number1687
Pages (from-to)1-10
Number of pages10
JournalMedicina
Volume60
Issue number10
DOIs
Publication statusPublished - 14 Oct 2024

Keywords*

  • optic nerve glioblastoma
  • Neurosurgery
  • Radiology
  • ophthalmology

Field of Science*

  • 3.2 Clinical medicine

Publication Type*

  • 1.1. Scientific article indexed in Web of Science and/or Scopus database

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