Abstract
Abstract: Background: optic nerve glioblastoma is an uncommon pathology. The optic chiasm, optic
tract, or optic nerves are possible places from which the tumor can originate. Most of the neuroimag-
ing findings are nonspecific. To confirm the diagnosis, a biopsy is required. A delay to the treatment
plan for optic nerve glioblastoma results in poor patient survival rates. Case report: a 68-year-old
woman with an uncomplicated medical history presented with exophthalmos, deteriorating eyesight,
and partial loss of vision. Using radiological data together with postoperative histopathological
and histochemical analysis, optic nerve glioblastoma, IDH-wildtype, with optic chiasm involvement
was diagnosed. Conclusion: optic nerve glioblastoma is a rare and aggressive form of cancer that
affects the optic nerve, leading to significant vision impairment and potentially life-threatening
complications. Treatment options are restricted and difficult because of the location and nature
of the condition; surgery, radiation therapy, and chemotherapy are frequently needed as part of a
multidisciplinary approach
tract, or optic nerves are possible places from which the tumor can originate. Most of the neuroimag-
ing findings are nonspecific. To confirm the diagnosis, a biopsy is required. A delay to the treatment
plan for optic nerve glioblastoma results in poor patient survival rates. Case report: a 68-year-old
woman with an uncomplicated medical history presented with exophthalmos, deteriorating eyesight,
and partial loss of vision. Using radiological data together with postoperative histopathological
and histochemical analysis, optic nerve glioblastoma, IDH-wildtype, with optic chiasm involvement
was diagnosed. Conclusion: optic nerve glioblastoma is a rare and aggressive form of cancer that
affects the optic nerve, leading to significant vision impairment and potentially life-threatening
complications. Treatment options are restricted and difficult because of the location and nature
of the condition; surgery, radiation therapy, and chemotherapy are frequently needed as part of a
multidisciplinary approach
Original language | English |
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Article number | 1687 |
Pages (from-to) | 1-10 |
Number of pages | 10 |
Journal | Medicina |
Volume | 60 |
Issue number | 10 |
DOIs | |
Publication status | Published - 14 Oct 2024 |
Keywords*
- optic nerve glioblastoma
- Neurosurgery
- Radiology
- ophthalmology
Field of Science*
- 3.2 Clinical medicine
Publication Type*
- 1.1. Scientific article indexed in Web of Science and/or Scopus database