Optical anisotropy of cell nuclei

Tālivaldis Freivalds, Valerie Groma, Indulis Buiķis

Research output: Contribution to journalConference articlepeer-review

1 Citation (Scopus)


Optical anisotropy in cell nuclei are associated with a subcellular organisation of nucleus. The differences in a breast adenocarcinomas toluidine blue stained chromatin birefringence intensity indicate differences in the chromatin Stereoarrangement in cell nuclei. In unstained paraffin sections origin of cell nuclei birefringence could be due to nonhistone proteins which appropriate conformational state developed during the paraffin embedding procedure. The unstained paraffin section cell nuclei birefringence could be useful optical feature for survival prognosis of patients with cancer.

Original languageEnglish
Pages (from-to)187-188
Number of pages2
JournalMedical and Biological Engineering and Computing
Issue numberSuppl. 1
Publication statusPublished - 1996
Externally publishedYes
Event10th Nordic-Baltic Conference on Biomedical Engineering - Tampere, Finland
Duration: 9 Jun 199613 Jun 1996
Conference number: 10

Field of Science*

  • 2.6 Medical engineering
  • 3.1 Basic medicine

Publication Type*

  • 1.1. Scientific article indexed in Web of Science and/or Scopus database


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