TY - JOUR
T1 - Organ printing
T2 - From bioprinter to organ biofabrication line
AU - Mironov, Vladimir
AU - Kasyanov, Vladimir
AU - Markwald, Roger R.
N1 - Funding Information:
This work was funded by NSF R-II grant ‘South Carolina Project for Organ Biofabrication’ .
PY - 2011/10
Y1 - 2011/10
N2 - Organ printing, or the layer by layer additive robotic biofabrication of functional three-dimensional tissue and organ constructs using self-assembling tissue spheroid building blocks, is a rapidly emerging technology that promises to transform tissue engineering into a commercially successful biomedical industry. It is increasingly obvious that similar well-established industries implement automated robotic systems on the path to commercial translation and economic success. The use of robotic bioprinters alone however is not sufficient for the development of large industrial scale organ biofabrication. The design and development of a fully integrated organ biofabrication line is imperative for the commercial translation of organ printing technology. This paper presents recent progress and challenges in the development of the essential components of an organ biofabrication line.
AB - Organ printing, or the layer by layer additive robotic biofabrication of functional three-dimensional tissue and organ constructs using self-assembling tissue spheroid building blocks, is a rapidly emerging technology that promises to transform tissue engineering into a commercially successful biomedical industry. It is increasingly obvious that similar well-established industries implement automated robotic systems on the path to commercial translation and economic success. The use of robotic bioprinters alone however is not sufficient for the development of large industrial scale organ biofabrication. The design and development of a fully integrated organ biofabrication line is imperative for the commercial translation of organ printing technology. This paper presents recent progress and challenges in the development of the essential components of an organ biofabrication line.
UR - http://www.scopus.com/inward/record.url?scp=80053384750&partnerID=8YFLogxK
UR - https://reader.elsevier.com/reader/sd/pii/S0958166911000334?token=EA959CAF88B572A969BC353B9EB934FE8D0FC175A06C74AC7551E67833C65AE8B65F15B13C1472613350C49A5C24548C&originRegion=eu-west-1&originCreation=20210714072116
U2 - 10.1016/j.copbio.2011.02.006
DO - 10.1016/j.copbio.2011.02.006
M3 - Review article
C2 - 21419621
AN - SCOPUS:80053384750
SN - 0958-1669
VL - 22
SP - 667
EP - 673
JO - Current Opinion in Biotechnology
JF - Current Opinion in Biotechnology
IS - 5
ER -