Organ printing: From bioprinter to organ biofabrication line

Vladimir Mironov, Vladimir Kasyanov, Roger R. Markwald

Research output: Contribution to journalReview articlepeer-review

301 Citations (Scopus)

Abstract

Organ printing, or the layer by layer additive robotic biofabrication of functional three-dimensional tissue and organ constructs using self-assembling tissue spheroid building blocks, is a rapidly emerging technology that promises to transform tissue engineering into a commercially successful biomedical industry. It is increasingly obvious that similar well-established industries implement automated robotic systems on the path to commercial translation and economic success. The use of robotic bioprinters alone however is not sufficient for the development of large industrial scale organ biofabrication. The design and development of a fully integrated organ biofabrication line is imperative for the commercial translation of organ printing technology. This paper presents recent progress and challenges in the development of the essential components of an organ biofabrication line.

Original languageEnglish
Pages (from-to)667-673
Number of pages7
JournalCurrent Opinion in Biotechnology
Volume22
Issue number5
DOIs
Publication statusPublished - Oct 2011

Field of Science*

  • 1.6 Biological sciences
  • 2.6 Medical engineering

Publication Type*

  • 1.1. Scientific article indexed in Web of Science and/or Scopus database

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