Outcomes of surgical correction of congenital tibia pseudarthrosis depending on the activation of HHV-6/HHV-7 viral infection in a child with neurofibromatosis type-1

A. Vilks, Dzintars Ozols, Viesturs Boka, Modra Murovska, Biruta Mamaja

Research output: Contribution to journalArticlepeer-review

Abstract

Neurofibromatosis type-1 (NF-1) -is a common genetic disease effecting the skin, subcutaneous tissue peripheral nerves and bones (tibia pseudarthrosis). Immunomodulatory viruses HHV-6 and HHV-7 are classibdng as a genus of roseoloviruses of subfamily fl-herpesviruses. Reactivation of HHV-6 and HHV-7 inhibits immune system and indirectly promote to other infectious agents. The article deals with a unique case repot of two repeated transplantations offibula due to congenital tibia pseudarthrosis caused by-NF-J. Results of the transplantations, related to active and latent HHV6 and HHV-7 infection in a 6 years old child are discussed in the paper.
Translated title of the contributionOutcomes of surgical correction of congenital tibia pseudarthrosis depending on the activation of HHV-6/HHV-7 viral infection in a child with neurofibromatosis type-1
Original languageRussian
Pages (from-to)61-63
JournalАнестезиология и Pеаниматология = Anesteziologiya i Reanimatologiya
Issue number1
Publication statusPublished - 2014

Keywords*

  • neurofibromatosis
  • HHV-6
  • HHV-7
  • activeinfection
  • latentinfection

Field of Science*

  • 3.2 Clinical medicine

Publication Type*

  • 1.1. Scientific article indexed in Web of Science and/or Scopus database

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