Overlaps in the Pathogenesis of Rosacea and Atherosclerosis

Research output: Contribution to journalArticlepeer-review

Abstract

Rosacea is a chronic inflammatory skin disease characterised by transient or persistent erythema, telangiectasia, papules, and pustules that predominantly involve central regions of the face. Recent studies have shown a possible clinical association between rosacea and cardiovascular diseases (CVDs). Rosacea and atherosclerosis are both known to have alterations in the innate immune system, enhanced oxidative and endoplasmic reticulum stress. The aim of this review is to delve deep into the pathogenesis of rosacea and atherosclerosis to uncover possible pathogenic overlaps between these chronic inflammatory diseases.

Original languageEnglish
Pages (from-to)152-159
Number of pages8
JournalProceedings of the Latvian Academy of Sciences, Section B: Natural, Exact, and Applied Sciences
Volume72
Issue number3
DOIs
Publication statusPublished - 1 Jun 2018

Keywords*

  • atherosclerosis
  • endoplasmic reticulum stress
  • LL-37
  • oxidative stress
  • rosacea
  • Toll-like receptor 2

Field of Science*

  • 3.2 Clinical medicine

Publication Type*

  • 1.1. Scientific article indexed in Web of Science and/or Scopus database

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