Pediatric renal replacement therapy: 20 years' experience in Pediatric Intensive Care Unit at Children’s Clinical University Hospital in Riga, Latvia

To introduce with retrospective data and experience that Children’s Clinical University hospital in Riga, Latvia have gained during last 20 years in cases were acute pediatric dialysis have been performed. A retrospective study with comparative analysis of all patients hospitalised from 1998 to 2018 (excluding year 2002) with renal replacement therapy in Children’s Clinical University hospital in pediatric intensive care unit.From overall 15 956 patients, that were hospitalised in pediatric intensive care unit, 167 received pediatric renal replacement therapy (peritoneal dialysis, continuous renal replacement therapy or both) and could be included in the study. Data were collected and analysed with Microsoft Excel. From 167 patients that underwent renal replacement therapy, 51% (n=86) was female gender, 49% (n=81) – male. All patients, that were included in the study, was divided into three age groups – younger then 1 year old (21%, n=36), 1 to 12 years old (56%, n=95), older then 12 years (21%, n=36). In the biggest part of cases 85,63% (n= 143) continuous renal replacement therapy were the method of choice, while in 13,77% (n=23) - peritoneal dyalisis was used. Only in one case combination of peritoneal dyalisis and continuous renal replacement therapy was used.Overall mortality data showed that 13% (n=21) of cases ended with exitus letalis. Looking closer to mortality rate in each age group, children < 1 y.o. 19% (n=7) cases ended with exitus letalis, while in children aged 1 – 12 y.o. – 11% (n=10), > 12 y.o. – 11% (n=4). Mortality rate was higher in continuous renal replacement therapy group 14% (n=20), while in peritoneal dialysis group mortality rate was lower – 4% (n=1). This study describes current overall renal replacement therapy use in pediatric population in Latvia. For more detailed data (common causes, length of RRT) study should be continued.