Pillar tarsoconjunctival flap: An alternative approach for the management of refractory corneal ulcer

Francisco Zamorano-Martin, Carlos Rocha-de-Lossada, Marina Rodriguez-Calvo-de-Mora, Juan Carlos Sanchez-España, Maria Garcia-Lorente (Coresponding Author), Davide Borroni, Jorge Peraza-Nieves, Santiago Ortiz-Perez, Josep Torras-Sanvicens

    Research output: Contribution to journalArticlepeer-review

    2 Citations (Scopus)


    Purpose: To report the effectiveness of the surgical procedure of the tarsoconjunctival flap (FTC) in patients with severe ocular surface impairment refractory to previous conventional treatments. Methods: A retrospective, noncomparative, consecutive case series. Results: Pillar tarsoconjunctival flap (PTCF) was performed in eight eyes of eight patients. Three patients had neurotrophic corneal ulcer (NCU), three had exposure keratopathy and two had corneal melting. Seven of them had satisfactory postoperative results, showing total corneal re-epithelialization that lasted throughout the postoperative follow-up (mean 10.33 ± 2.65 months [SD], range 6 to 12 months). Mean time for the re-epithelization was 11.28 ± 8.97 days [SD] (range 4 to 30 days). Conclusion: This study suggest PTCF is a valid alternative to tarsorrhaphy in cases of persistent epithelial defect (PED) or NCU resistant to conventional treatments. Notwithstanding, prospective comparative trials comparing PTFC with conventional and/or novel therapies in PED or NCU are needed to corroborate these findings.

    Original languageEnglish
    Pages (from-to)3383-3391
    Number of pages9
    JournalEuropean Journal of Ophthalmology
    Issue number6
    Publication statusPublished - Nov 2022


    • blinking phenomenon
    • corneal melting
    • exposure keratopathy
    • neurotrophic keratopathy
    • ocular surface
    • Pillar tarsoconjunctival flap
    • tarsorrhaphy

    Field of Science*

    • 3.2 Clinical medicine

    Publication Type*

    • 1.1. Scientific article indexed in Web of Science and/or Scopus database


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