Placental volume in the first trimester: correlation with biochemical placenta parameters and uterine artery Doppler

Research output: Contribution to journalMeeting Abstractpeer-review

Abstract

Objectives
The aim of our study was to evaluate the correlation between placental volume (PV), and uterine artery (UtA) Doppler velocimetry and such placental functional indices as PAPPA, free BHCG and in the first trimester of pregnancy.

Methods
111 women undergoing first trimester screening were prospectively assessed using 3D ultrasound in order to measure PV using the VOCAL software (Voluson E8, GE). The offline analysis was performed by 4D view software and PV was calculated using VOCAL option (85°). Placental quotient (PQ) was calculated by dividing PV by the fetal Crown–rump length (CRL). Spearman's correlation coefficient (ρ) between PV and PAPP-A, free BHCG, UtA mPI were calculated. In addition, PQ correlation with PAPP-A, free BHCG, UtA mPI was assessed. P < 0.05 was considered statistically significant.

Results
The mean placental volume was 73.8 mm3. There was a weak negative correlation between PV and UtA mPI (ρ = 0.22, P = 0.039, CI -0.1- -0.52). No correlation between PV and PAPP-A (ρ = 0.19, p = 0.13), free BHCG (ρ = 0.056, p = 0.61). No correlation between PQ and PAPP-A (ρ = 0.25, P = 0.13), free BHCG (ρ = 0.17, P = 0.21), or UtA mPI (ρ = 0.23, P = 0.11) were found.

Conclusions
In our study we found a weak negative correlation between placental volume and uterine artery velocimetry. Therefore, we plan to compare placental volume and uterine artery prediction power for PE and IUGR when the outcomes become available.
Original languageEnglish
Pages (from-to)273-274
JournalUltrasound in Obstetrics and Gynecology
Volume58
Issue numberSuppl.1
DOIs
Publication statusPublished - 14 Oct 2021
Event31st World Congress on Ultrasound in Obstetrics and Gynecology - Virtual
Duration: 15 Oct 202118 Oct 2021
Conference number: 31
https://www.isuog.org/events/past-events/world-congress-2021.html

Field of Science*

  • 3.2 Clinical medicine

Publication Type*

  • 3.4. Other publications in conference proceedings (including local)

Fingerprint

Dive into the research topics of 'Placental volume in the first trimester: correlation with biochemical placenta parameters and uterine artery Doppler'. Together they form a unique fingerprint.

Cite this