Plasma Rich in Growth Factors (PRGF) in Transepithelial Photorefractive Keratectomy (TPRK)

Jose-Maria Sanchez-Gonzalez; Federico Alonso-Aliste; Davide Borroni; Jonatan Amian-Cordero; Concepcion De-Hita-Cantalejo; Raul Capote-Puente; Maria-Jose Bautista-Llamas; Maria Carmen Sanchez-Gonzalez; Marina Rodriguez-Calvo-de-Mora; Carlos Rocha-de-Lossada

doi:10.3390/jcm10091939

Plasma Rich in Growth Factors (PRGF) in Transepithelial Photorefractive Keratectomy (TPRK)

Jose-Maria Sanchez-Gonzalez (Corresponding Author), Federico Alonso-Aliste, Davide Borroni, Jonatan Amian-Cordero, Concepcion De-Hita-Cantalejo, Raul Capote-Puente, Maria-Jose Bautista-Llamas, Maria Carmen Sanchez-Gonzalez, Marina Rodriguez-Calvo-de-Mora, Carlos Rocha-de-Lossada

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Abstract

To evaluate the usage of plasma rich in growth factor (PRGF) in transepithelial photorefractive keratectomy (TPRK) in low and moderate myopia, patients who underwent myopic and
astigmatism TPRK with PRGF were involved in this retrospective, observational study. Subjects
underwent a surgical procedure between February 2019 and June 2019. A three-month follow-up
was recorded. Pain score was assessed with a visual analogue scale (0–10) and re-epithelialization
time recorded. A total of 48 eyes from 24 patients were recruited. Mean uncorrected distance visual
acuity (UDVA) was 20/20.31 (0.00 ± 0.02 LogMAR). A total of 98% of eyes did not change corrected
distance visual acuity (CDVA) lines. Two percent of eyes lost one line of CDVA. Preoperative spherical equivalent was −2.67 ± 1.37 D and after three months changed to −0.21 ± 0.34 D, and 2% of
eyes changed 0.50 D or more between one and three months. Pain score was 3.29 ± 0.61 (3 to 6)
score points at day one and 0.08 ± 0.27 score points at day seven. Finally, re-epithelialization time
was 2.50 ± 1.20 days. PRGF addition to conventional refractive treatment such as TPRK seems to
alleviate immediate postoperative pain and positively contribute to corneal re-epithelization time.

Original language	English
Article number	1939
Number of pages	9
Journal	Journal of clinical medicine
Volume	10
Issue number	9
DOIs	https://doi.org/10.3390/jcm10091939
Publication status	Published - May 2021

Keywords*

plasma rich in growth factor
photorefractive keratectomy
transepithelial photorefractive keratectomy
visual outcomes
refractive outcomes

Field of Science*

3.2 Clinical medicine

Publication Type*

1.1. Scientific article indexed in Web of Science and/or Scopus database

Access to Document

10.3390/jcm10091939Licence: CC BY

Plasma Rich in Growth Factors (PRGF)Final published version, 713 KBLicence: CC BY

Cite this

Sanchez-Gonzalez, J.-M., Alonso-Aliste, F., Borroni, D., Amian-Cordero, J., De-Hita-Cantalejo, C., Capote-Puente, R., Bautista-Llamas, M.-J., Sanchez-Gonzalez, M. C., Rodriguez-Calvo-de-Mora, M., & Rocha-de-Lossada, C. (2021). Plasma Rich in Growth Factors (PRGF) in Transepithelial Photorefractive Keratectomy (TPRK). Journal of clinical medicine, 10(9), Article 1939. https://doi.org/10.3390/jcm10091939

@article{d0af0a473082492cb79bf72fe609d7a6,

title = "Plasma Rich in Growth Factors (PRGF) in Transepithelial Photorefractive Keratectomy (TPRK)",

abstract = "To evaluate the usage of plasma rich in growth factor (PRGF) in transepithelial photorefractive keratectomy (TPRK) in low and moderate myopia, patients who underwent myopic andastigmatism TPRK with PRGF were involved in this retrospective, observational study. Subjectsunderwent a surgical procedure between February 2019 and June 2019. A three-month follow-upwas recorded. Pain score was assessed with a visual analogue scale (0–10) and re-epithelializationtime recorded. A total of 48 eyes from 24 patients were recruited. Mean uncorrected distance visualacuity (UDVA) was 20/20.31 (0.00 ± 0.02 LogMAR). A total of 98% of eyes did not change correcteddistance visual acuity (CDVA) lines. Two percent of eyes lost one line of CDVA. Preoperative spherical equivalent was −2.67 ± 1.37 D and after three months changed to −0.21 ± 0.34 D, and 2% ofeyes changed 0.50 D or more between one and three months. Pain score was 3.29 ± 0.61 (3 to 6)score points at day one and 0.08 ± 0.27 score points at day seven. Finally, re-epithelialization timewas 2.50 ± 1.20 days. PRGF addition to conventional refractive treatment such as TPRK seems toalleviate immediate postoperative pain and positively contribute to corneal re-epithelization time.",

keywords = "plasma rich in growth factor, photorefractive keratectomy, transepithelial photorefractive keratectomy, visual outcomes, refractive outcomes",

author = "Jose-Maria Sanchez-Gonzalez and Federico Alonso-Aliste and Davide Borroni and Jonatan Amian-Cordero and Concepcion De-Hita-Cantalejo and Raul Capote-Puente and Maria-Jose Bautista-Llamas and Sanchez-Gonzalez, {Maria Carmen} and Marina Rodriguez-Calvo-de-Mora and Carlos Rocha-de-Lossada",

year = "2021",

month = may,

doi = "10.3390/jcm10091939",

language = "English",

volume = "10",

journal = "Journal of clinical medicine",

issn = "2077-0383",

publisher = "MDPI AG",

number = "9",

}

Sanchez-Gonzalez, J-M, Alonso-Aliste, F, Borroni, D, Amian-Cordero, J, De-Hita-Cantalejo, C, Capote-Puente, R, Bautista-Llamas, M-J, Sanchez-Gonzalez, MC, Rodriguez-Calvo-de-Mora, M & Rocha-de-Lossada, C 2021, 'Plasma Rich in Growth Factors (PRGF) in Transepithelial Photorefractive Keratectomy (TPRK)', Journal of clinical medicine, vol. 10, no. 9, 1939. https://doi.org/10.3390/jcm10091939

TY - JOUR

T1 - Plasma Rich in Growth Factors (PRGF) in Transepithelial Photorefractive Keratectomy (TPRK)

AU - Sanchez-Gonzalez, Jose-Maria

AU - Alonso-Aliste, Federico

AU - Borroni, Davide

AU - Amian-Cordero, Jonatan

AU - De-Hita-Cantalejo, Concepcion

AU - Capote-Puente, Raul

AU - Bautista-Llamas, Maria-Jose

AU - Sanchez-Gonzalez, Maria Carmen

AU - Rodriguez-Calvo-de-Mora, Marina

AU - Rocha-de-Lossada, Carlos

PY - 2021/5

Y1 - 2021/5

N2 - To evaluate the usage of plasma rich in growth factor (PRGF) in transepithelial photorefractive keratectomy (TPRK) in low and moderate myopia, patients who underwent myopic andastigmatism TPRK with PRGF were involved in this retrospective, observational study. Subjectsunderwent a surgical procedure between February 2019 and June 2019. A three-month follow-upwas recorded. Pain score was assessed with a visual analogue scale (0–10) and re-epithelializationtime recorded. A total of 48 eyes from 24 patients were recruited. Mean uncorrected distance visualacuity (UDVA) was 20/20.31 (0.00 ± 0.02 LogMAR). A total of 98% of eyes did not change correcteddistance visual acuity (CDVA) lines. Two percent of eyes lost one line of CDVA. Preoperative spherical equivalent was −2.67 ± 1.37 D and after three months changed to −0.21 ± 0.34 D, and 2% ofeyes changed 0.50 D or more between one and three months. Pain score was 3.29 ± 0.61 (3 to 6)score points at day one and 0.08 ± 0.27 score points at day seven. Finally, re-epithelialization timewas 2.50 ± 1.20 days. PRGF addition to conventional refractive treatment such as TPRK seems toalleviate immediate postoperative pain and positively contribute to corneal re-epithelization time.

AB - To evaluate the usage of plasma rich in growth factor (PRGF) in transepithelial photorefractive keratectomy (TPRK) in low and moderate myopia, patients who underwent myopic andastigmatism TPRK with PRGF were involved in this retrospective, observational study. Subjectsunderwent a surgical procedure between February 2019 and June 2019. A three-month follow-upwas recorded. Pain score was assessed with a visual analogue scale (0–10) and re-epithelializationtime recorded. A total of 48 eyes from 24 patients were recruited. Mean uncorrected distance visualacuity (UDVA) was 20/20.31 (0.00 ± 0.02 LogMAR). A total of 98% of eyes did not change correcteddistance visual acuity (CDVA) lines. Two percent of eyes lost one line of CDVA. Preoperative spherical equivalent was −2.67 ± 1.37 D and after three months changed to −0.21 ± 0.34 D, and 2% ofeyes changed 0.50 D or more between one and three months. Pain score was 3.29 ± 0.61 (3 to 6)score points at day one and 0.08 ± 0.27 score points at day seven. Finally, re-epithelialization timewas 2.50 ± 1.20 days. PRGF addition to conventional refractive treatment such as TPRK seems toalleviate immediate postoperative pain and positively contribute to corneal re-epithelization time.

KW - plasma rich in growth factor

KW - photorefractive keratectomy

KW - transepithelial photorefractive keratectomy

KW - visual outcomes

KW - refractive outcomes

U2 - 10.3390/jcm10091939

DO - 10.3390/jcm10091939

M3 - Article

SN - 2077-0383

VL - 10

JO - Journal of clinical medicine

JF - Journal of clinical medicine

IS - 9

M1 - 1939

ER -

Plasma Rich in Growth Factors (PRGF) in Transepithelial Photorefractive Keratectomy (TPRK)

Abstract

Keywords*

Field of Science*

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