Blood and erythrocytes of 50 healthy volunteers and 105 patients with different forms of hemoblastoses were investigated. 54 patients had acute phase, 51 patients--remission stage of disease. Essential differences in the activity of antioxidant enzymes (SOD, CAT, GSH-Px) were detected and compared with content of MDA and degree of anaemia. Acute phase had more significantly alteration of antioxidant defence: diverse changes of the activity of SOD and CAT, significantly inhibition of GSH-Px, the high level of MDA and increased degree of anaemia.
|Translated title of the contribution||Possible use of erythrocyte antioxidant enzymes as markers of the course of disease in patients with hemoblastoses|
|Number of pages||4|
|Journal||Voprosy Meditsinskoi Khimii|
|Publication status||Published - Apr 1996|
Field of Science*
- 3.1 Basic medicine
- 1.1. Scientific article indexed in Web of Science and/or Scopus database