Abstract
According to the literature, psoriasis patients have an increased risk of malignancy, especially in patients with severe psoriasis. Chronic inflammation is believed to be one of the risk factors linking psoriasis to malignancy.
Malignancy is most often an exclusion criterion in randomized clinical trials, so data from randomized trials are not available for this patient group and clinicians can obtain information from observations and real-world data studies.
Current data from population studies show that treatment with IL-17 and IL-23 inhibitors is associated with a reduced risk of several malignancies.
EuroGuiDerm Clinical Guidelines allow the use of biologics in psoriasis patients with malignant tumors. However, due to the lack of rigorous research data on the use of biological therapy in cancer patients, a decision on the use of therapy should be made on case-by-case basis, discussing with the patient and considering recommendations from the treating oncologist.
Malignancy is most often an exclusion criterion in randomized clinical trials, so data from randomized trials are not available for this patient group and clinicians can obtain information from observations and real-world data studies.
Current data from population studies show that treatment with IL-17 and IL-23 inhibitors is associated with a reduced risk of several malignancies.
EuroGuiDerm Clinical Guidelines allow the use of biologics in psoriasis patients with malignant tumors. However, due to the lack of rigorous research data on the use of biological therapy in cancer patients, a decision on the use of therapy should be made on case-by-case basis, discussing with the patient and considering recommendations from the treating oncologist.
Translated title of the contribution | Psoriasis in patients with oncological diseases |
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Original language | Latvian |
Pages | 41 |
Number of pages | 1 |
Publication status | Published - 9 Nov 2024 |
Externally published | Yes |
Event | LDVA 19TH Congress with International Participation “Latest Achievements in Dermatology, Venereology, Oncology and Aesthetics” - Riga, Riga, Latvia Duration: 8 Nov 2024 → 9 Nov 2024 Conference number: 19 https://ldva2024riga.org/en/ldva2024/ |
Congress
Congress | LDVA 19TH Congress with International Participation “Latest Achievements in Dermatology, Venereology, Oncology and Aesthetics” |
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Abbreviated title | LDVA |
Country/Territory | Latvia |
City | Riga |
Period | 8/11/24 → 9/11/24 |
Internet address |
Keywords*
- Psoriasis
Field of Science*
- 3.2 Clinical medicine
Publication Type*
- 3.4. Other publications in conference proceedings (including local)