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Radiological Findings of Retrograde Venous Cerebral Air Embolism Infarcts: A Case Report and Literature Review

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Abstract

Background: Cerebral air embolism infarction (CAEI) is a rare but life-threatening condition that can affect the venous or arterial
blood supply to the brain. Its aetiology is mostly iatrogenic, often resulting from complications of cardiothoracic or neurosurgical
procedures, as well as manipulations with peripheral or central catheters. If undiagnosed and untreated, cerebral air embolism
infarction can lead to long-term neurological consequences or even death. Diagnosis relies on clinical presentation and neuroimaging
findings from CT and MRI, which are time-sensitive and not well described in the current literature.
Case Presentation: We present a rare case of cerebral infarction as a complication of retrograde cerebral venous air embolism
following haemodialysis catheter removal in a young patient, with management leading to a favourable outcome. The diagnosis was
confirmed based on clinical manifestations and neuroimaging findings, with air emboli identified in the subarachnoid space on the CT
scan, followed by characteristic MRI changes defined for cerebral air embolism infarcts. Timely diagnosis allowed for the rapid
initiation of hyperbaric oxygen therapy and the rehabilitation process, resulting in positive outcomes.
Conclusion: Timely neuroimaging—particularly CT within the first 2 hours—is critical for diagnosing CAEI. MRI findings,
including cytotoxic and vasogenic oedema in a distal vascular distribution and leptomeningeal enhancement, further support diagnosis.
Early identification and treatment initiation are essential for improving patient outcomes
Original languageEnglish
Pages (from-to)617–631
Number of pages15
JournalVascular Health and Risk Management
Volume21
DOIs
Publication statusPublished - 11 Aug 2025

Keywords*

  • cerebral air/gas embolism infarction
  • retrograde air/gas venous emboli
  • hemodialysis
  • hyperbaric oxygen therapy
  • MRI

Field of Science*

  • 3.2 Clinical medicine

Publication Type*

  • 1.1. Scientific article indexed in Web of Science and/or Scopus database

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