Abstract
Objective: Rare disease
Background: Meningiomas stand as the predominant primary intracranial tumors, encompassing a broad spectrum of histological variations. Within this spectrum, angiomatous meningiomas are notable for their significant vascularity within the tumor structure and rarity, making up only 2.1% of all meningiomas. These tumors typically
present with slow-onset symptoms, commonly manifesting as seizures and compression-related effects. This
report describes a 27-year-old man presenting with seizures and a diagnosis of angiomatous meningioma with
postoperative recurrence, emphasizing the challenges in imaging, diagnosis, and disease management.
Case Report: A 27-year-old man presented with a generalized seizure and unconsciousness. He had a history of exposure to
chemicals from road construction and logging and smoked for 7 pack years. Initial CT scan revealed a 2.8-cm
irregular tumor on the convex surface of his right frontal lobe. Craniotomy and resection of the lesion revealed
angiomatous meningioma (central nervous system [CNS] World Health Organization [WHO] grade I). Six months
later, control MRI showed recurrence at the excision site (2.4×2.0×1.4 cm). Re-craniotomy confirmed atypical
meningioma (CNS WHO grade 2), and the patient received postoperative radiotherapy (56 Gy).
Conclusions: This case report highlights the importance of MRI in diagnosing angiomatous meningioma, a rare subtype comprising only 2.1% of all meningiomas. Although the tumor was initially resected successfully, its rapid recurrence as a WHO grade 2 atypical meningioma within 6 months underscores the surgical challenges and high
recurrence risk associated with its vascular nature. These findings emphasize the need for careful postoperative monitoring and management.
Background: Meningiomas stand as the predominant primary intracranial tumors, encompassing a broad spectrum of histological variations. Within this spectrum, angiomatous meningiomas are notable for their significant vascularity within the tumor structure and rarity, making up only 2.1% of all meningiomas. These tumors typically
present with slow-onset symptoms, commonly manifesting as seizures and compression-related effects. This
report describes a 27-year-old man presenting with seizures and a diagnosis of angiomatous meningioma with
postoperative recurrence, emphasizing the challenges in imaging, diagnosis, and disease management.
Case Report: A 27-year-old man presented with a generalized seizure and unconsciousness. He had a history of exposure to
chemicals from road construction and logging and smoked for 7 pack years. Initial CT scan revealed a 2.8-cm
irregular tumor on the convex surface of his right frontal lobe. Craniotomy and resection of the lesion revealed
angiomatous meningioma (central nervous system [CNS] World Health Organization [WHO] grade I). Six months
later, control MRI showed recurrence at the excision site (2.4×2.0×1.4 cm). Re-craniotomy confirmed atypical
meningioma (CNS WHO grade 2), and the patient received postoperative radiotherapy (56 Gy).
Conclusions: This case report highlights the importance of MRI in diagnosing angiomatous meningioma, a rare subtype comprising only 2.1% of all meningiomas. Although the tumor was initially resected successfully, its rapid recurrence as a WHO grade 2 atypical meningioma within 6 months underscores the surgical challenges and high
recurrence risk associated with its vascular nature. These findings emphasize the need for careful postoperative monitoring and management.
| Original language | English |
|---|---|
| Article number | e947185 |
| Journal | American Journal of Case Reports |
| Volume | 26 |
| DOIs | |
| Publication status | Published - 15 Apr 2025 |
Keywords*
- Angiomatosis
- Central Nervous System
- Magnetic Resonance Imaging
- Meningioma
- Oncology Service
Field of Science*
- 3.2 Clinical medicine
- 3.1 Basic medicine
Publication Type*
- 1.4. Reviewed scientific article published in Latvia or abroad in a scientific journal with an editorial board (including university editions)