Acute appendicitis is the common cause of emergency surgery in children and appendectomy remains the treatment of choice for most paediatric patients. Last decade showed evidence of nonoperative treatment of acute uncomplicated appendicitis cases. It may be safe and effective in selected children, however, there is a lack in clinical guidance of nonoperative management, especially in selection of analgesic agent and pain control.The objective of this study was to search, identify and review clinical studies related to selected topic. The search in on-line medical data bases PubMed and Medline was performed, using further mentioned key phrases in different combinations: "pain control", "pain assessment","analgesia", "uncomplicated acute appendicitis", "nonoperative treatment", "nonsurgical treatment", "conservative treatment", "nonoperative management", "children". As a result of search 15 articles were identified. 7 of 15 studies were related to selected topic of pain control regimens as a part of nonoperative management of uncomplicated acute appendicitis in children. Only in 2 out of 7 studies pain control regimen was reported and specified. But only in one (Paudel GR, Agrawal CS, Agrawal S. Conservative treatment in acute appendicitis. J Nepal Med Assoc. 2010:50(180):295-299.) of two last studies pain assessment, control regimen and extent of analgesia were reported and specified. Despite growing popularity in nonoperative management of uncomplicated acute appendicitis in children, there is still a huge lack of evidence-based studies on pain assessment, control and extent of analgesia.
Authors has proposed the clinical trial in Children's clinical university hospital to find a correlation between pain syndrome and inflammatory parameters in 7 to 17 years old paediatric patients with acute uncomplicated appendicitis recieving nonoperative treatment. Expected results of this study may help decision-making in choice of analgesia for children with nonoperative management of acute uncomplicated appendicitis.
- 3.4. Other publications in conference proceedings (including local)