Abstract
Objective: Pulmonary embolism, although frequently a clinically silent
phenomenon, still causes a fairly stable incidence of sudden death. Fat
and marrow embolism usually appears after long bone fractures. The aim
of the report is to present a case of pulmonary bone marrow embolism
after cardiopulmonary resuscitation.
Method: A 63-year-old female died unexpectedly with symptoms of
cardio-respiratory failure after acute bleeding from duodenal ulcers.
During recent years, she was repeatedly admitted to hospital because of
upper gastrointestinal bleeding. An autopsy was performed.
Results: Autopsy disclosed multiple chronic duodenal ulcers in active
and remission phases, as well as gastritis and duodenitis. Right-sided
struvite-type kidney stones clinically correlated with severely decreased
glomerular filtration rate and elevated creatinine level corresponding to
chronic kidney disease. A component of acute kidney failure was noted.
The gross fractures of two ribs and microscopical finding of pulmonary
bone marrow embolism in small and medium-sized blood vessels were
attributable to cardiopulmonary resuscitation.
Conclusion: Cardiopulmonary resuscitation-related rib fracture can
cause pulmonary bone marrow embolism that has basically no importance as an autopsy finding. It may be considered a complication in
patients with successful reanimation. Resuscitation-related pulmonary
bone marrow embolism represents an important differential diagnosis to
forensic traumatic death causes.
phenomenon, still causes a fairly stable incidence of sudden death. Fat
and marrow embolism usually appears after long bone fractures. The aim
of the report is to present a case of pulmonary bone marrow embolism
after cardiopulmonary resuscitation.
Method: A 63-year-old female died unexpectedly with symptoms of
cardio-respiratory failure after acute bleeding from duodenal ulcers.
During recent years, she was repeatedly admitted to hospital because of
upper gastrointestinal bleeding. An autopsy was performed.
Results: Autopsy disclosed multiple chronic duodenal ulcers in active
and remission phases, as well as gastritis and duodenitis. Right-sided
struvite-type kidney stones clinically correlated with severely decreased
glomerular filtration rate and elevated creatinine level corresponding to
chronic kidney disease. A component of acute kidney failure was noted.
The gross fractures of two ribs and microscopical finding of pulmonary
bone marrow embolism in small and medium-sized blood vessels were
attributable to cardiopulmonary resuscitation.
Conclusion: Cardiopulmonary resuscitation-related rib fracture can
cause pulmonary bone marrow embolism that has basically no importance as an autopsy finding. It may be considered a complication in
patients with successful reanimation. Resuscitation-related pulmonary
bone marrow embolism represents an important differential diagnosis to
forensic traumatic death causes.
Original language | English |
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Article number | E-PS-15-007 |
Pages (from-to) | S339-S339 |
Number of pages | 1 |
Journal | Virchows Archiv |
Volume | 471 |
Issue number | Suppl. 1 |
Publication status | Published - Sept 2017 |
Event | 29th European Congress of Pathology: Pathology for patient care - Amsterdam, Netherlands Duration: 2 Sept 2017 → 6 Sept 2017 Conference number: 29 https://pathology.nl/evenement/29th-european-congress-of-pathology/ https://www.esp-congress.org/_Resources/Persistent/c6589e10208b86a3700a8c1f36aca4325f15f3a4/ECP2017_Final%20Programme.pdf |
Field of Science*
- 3.1 Basic medicine
Publication Type*
- 3.3. Publications in conference proceedings indexed in Web of Science and/or Scopus database