@article{c06eeb8ca4f4493f936d7d8ef63fbc86,
title = "Silver- and/or titanium-doped β-tricalcium phosphate bioceramic with antibacterial activity against Staphylococcus aureus",
abstract = "Ag- and/or Ti-doped apatitic-tricalcium phosphate powders were synthesized by wet chemical precipitation method. Regardless of the element composition, calcination of the Ag- and/or Ti-doped apatitic tricalcium phosphate powders at 900 °C gave phase-pure β-tricalcium phosphate. Cumulative release of Ca(II) and Ag(I) ions in TRIS-HCl buffer solution was determined. Increase of the solubility of the β-tricalcium phosphate was observed with the addition of Ti. Furthermore, prolonged (up to 28 days) release of the Ag(I) ions from the Ag-doped and the Ag- and Ti-co-doped β-tricalcium phosphate was observed. Minimum inhibitory concentration and antibacterial activity of the Ag- and/or Ti-doped β-tricalcium phosphate powders against Gram-positive Staphylococcus aureus was determined. It was observed that the addition of both, Ti and Ag, confers antibacterial properties of the β-tricalcium phosphate against Staphylococcus aureus.",
keywords = "Ag-/Ti-doping, Antibacterial properties, Bioceramics, β-tricalcium phosphate",
author = "Liga Stipniece and Ingus Skadins and Marika Mosina",
note = "Funding Information: The authors acknowledge financial support from the European Union's Horizon 2020 research and innovation programme under the grant agreement No. 857287 . Funding Information: This work has been supported by the European Regional Development Fund within the Activity 1.1.1.2 ?Post-doctoral Research Aid? of the Specific Aid Objective 1.1.1 ?To increase the research and innovative capacity of scientific institutions of Latvia and the ability to attract external financing, investing in human resources and infrastructure? of the Operational Programme ?Growth and Employment? (No. 1.1.1.2/VIAA/2/18/339). The authors acknowledge financial support from the European Union's Horizon 2020 research and innovation programme under the grant agreement No. 857287. Funding Information: This work has been supported by the European Regional Development Fund within the Activity 1.1.1.2 “Post-doctoral Research Aid” of the Specific Aid Objective 1.1.1 “To increase the research and innovative capacity of scientific institutions of Latvia and the ability to attract external financing, investing in human resources and infrastructure” of the Operational Programme “Growth and Employment” (No. 1.1.1.2/VIAA/2/18/339). Publisher Copyright: {\textcopyright} 2021 Elsevier Ltd and Techna Group S.r.l.",
year = "2022",
month = apr,
day = "1",
doi = "10.1016/j.ceramint.2021.12.232",
language = "English",
volume = "48",
pages = "10195--10201",
journal = "Ceramics International",
issn = "0272-8842",
publisher = "Elsevier Ltd.",
number = "7",
}