SINGLE-CENTRE STUDY: MIS-C IMPACT ON BLOOD PRESSURE, CORONARY ARTERIES AND LEFT VENTRICULAR FUNCTION

Emīls Šmitiņš; Dace Gardovska; Ingūna Lubaua; Inga Lāce; Elīna Ligere; Inta Bergmane; Baiba Matsone-Matsate; Pauls Sīlis; Luīze Auziņa; Ieva Kravale

Abstract

BACKGROUND AND AIM: MIS-C is a hyperinflammatory syndrome caused by Sars-CoV-2 virus. Cardiovascular system impairment is observed up to 100 % of all MIS-C patients with a wide spectrum and severity of symptoms. It is important to identify the course of the disease and its outcome, which could significantly improve public health.
METHODS: A single-centre study, prospective cohort study, conducted in the Children’s Clinical University hospital in Latvia from January to December 2021. Patients between the ages of one to seventeen years who met the MIS-C criteria were included in the study. We evaluated blood pressure, left ventricular heart function, size of coronary arteries and hospital course.
RESULTS: Thirty-one patients were included who met the MIS-C criteria. The median age was 8.0 years, 52% were boys. Of all patients 77% initially presented with hypotension of whom 42% required inotropic support. Treatment in PICU was required in 58% of all patients. Reduced left ventricular ejection fraction was observed in 35% of all patients. Mildly decreased ventricular ejection fraction (

Original language	English
Pages	701
Number of pages	1
Publication status	Published - 25 May 2022
Event	55th Annual Meeting of the Association for European Pediatric and Congenital Cardiology (AEPC) - Geneva, Switzerland Duration: 25 May 2022 → 28 May 2022 Conference number: 55 https://www.aepc.org/aepc-annual-meeting https://conferencealerts.com/show-event?id=240395

Meeting

Meeting	55th Annual Meeting of the Association for European Pediatric and Congenital Cardiology (AEPC)
Abbreviated title	AEPC 2022
Country/Territory	Switzerland
City	Geneva
Period	25/05/22 → 28/05/22
Internet address	https://www.aepc.org/aepc-annual-meeting https://conferencealerts.com/show-event?id=240395

Keywords*

MIS-C
Hypotension
coronary artery dilation

Field of Science*

3.2 Clinical medicine

Publication Type*

3.4. Other publications in conference proceedings (including local)

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Cite this

Šmitiņš, E., Gardovska, D., Lubaua, I., Lāce, I., Ligere, E., Bergmane, I., Matsone-Matsate, B., Sīlis, P., Auziņa, L., & Kravale, I. (2022). SINGLE-CENTRE STUDY: MIS-C IMPACT ON BLOOD PRESSURE, CORONARY ARTERIES AND LEFT VENTRICULAR FUNCTION. 701. Abstract from 55th Annual Meeting of the Association for European Pediatric and Congenital Cardiology (AEPC), Geneva, Switzerland.

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title = "SINGLE-CENTRE STUDY: MIS-C IMPACT ON BLOOD PRESSURE, CORONARY ARTERIES AND LEFT VENTRICULAR FUNCTION",

abstract = "BACKGROUND AND AIM: MIS-C is a hyperinflammatory syndrome caused by Sars-CoV-2 virus. Cardiovascular system impairment is observed up to 100 % of all MIS-C patients with a wide spectrum and severity of symptoms. It is important to identify the course of the disease and its outcome, which could significantly improve public health. METHODS: A single-centre study, prospective cohort study, conducted in the Children{\textquoteright}s Clinical University hospital in Latvia from January to December 2021. Patients between the ages of one to seventeen years who met the MIS-C criteria were included in the study. We evaluated blood pressure, left ventricular heart function, size of coronary arteries and hospital course. RESULTS: Thirty-one patients were included who met the MIS-C criteria. The median age was 8.0 years, 52% were boys. Of all patients 77% initially presented with hypotension of whom 42% required inotropic support. Treatment in PICU was required in 58% of all patients. Reduced left ventricular ejection fraction was observed in 35% of all patients. Mildly decreased ventricular ejection fraction (",

keywords = "MIS-C, Hypotension, coronary artery dilation",

author = "Emīls {\v S}mitiņ{\v s} and Dace Gardovska and Ingūna Lubaua and Inga Lāce and Elīna Ligere and Inta Bergmane and Baiba Matsone-Matsate and Pauls Sīlis and Luīze Auziņa and Ieva Kravale",

year = "2022",

month = may,

day = "25",

language = "English",

pages = "701",

note = "55th Annual Meeting of the Association for European Pediatric and Congenital Cardiology (AEPC), AEPC 2022 ; Conference date: 25-05-2022 Through 28-05-2022",

url = "https://www.aepc.org/aepc-annual-meeting, https://conferencealerts.com/show-event?id=240395",

}

Šmitiņš, E , Gardovska, D , Lubaua, I , Lāce, I , Ligere, E, Bergmane, I, Matsone-Matsate, B, Sīlis, P , Auziņa, L & Kravale, I 2022, 'SINGLE-CENTRE STUDY: MIS-C IMPACT ON BLOOD PRESSURE, CORONARY ARTERIES AND LEFT VENTRICULAR FUNCTION', 55th Annual Meeting of the Association for European Pediatric and Congenital Cardiology (AEPC), Geneva, Switzerland, 25/05/22 - 28/05/22 pp. 701.

SINGLE-CENTRE STUDY: MIS-C IMPACT ON BLOOD PRESSURE, CORONARY ARTERIES AND LEFT VENTRICULAR FUNCTION. / Šmitiņš, Emīls ; Gardovska, Dace ; Lubaua, Ingūna et al.
2022. 701 Abstract from 55th Annual Meeting of the Association for European Pediatric and Congenital Cardiology (AEPC), Geneva, Switzerland.

Research output: Contribution to conference › Abstract › peer-review

TY - CONF

T1 - SINGLE-CENTRE STUDY: MIS-C IMPACT ON BLOOD PRESSURE, CORONARY ARTERIES AND LEFT VENTRICULAR FUNCTION

AU - Šmitiņš, Emīls

AU - Gardovska, Dace

AU - Lubaua, Ingūna

AU - Lāce, Inga

AU - Ligere, Elīna

AU - Bergmane, Inta

AU - Matsone-Matsate, Baiba

AU - Sīlis, Pauls

AU - Auziņa, Luīze

AU - Kravale, Ieva

N1 - Conference code: 55

PY - 2022/5/25

Y1 - 2022/5/25

N2 - BACKGROUND AND AIM: MIS-C is a hyperinflammatory syndrome caused by Sars-CoV-2 virus. Cardiovascular system impairment is observed up to 100 % of all MIS-C patients with a wide spectrum and severity of symptoms. It is important to identify the course of the disease and its outcome, which could significantly improve public health. METHODS: A single-centre study, prospective cohort study, conducted in the Children’s Clinical University hospital in Latvia from January to December 2021. Patients between the ages of one to seventeen years who met the MIS-C criteria were included in the study. We evaluated blood pressure, left ventricular heart function, size of coronary arteries and hospital course. RESULTS: Thirty-one patients were included who met the MIS-C criteria. The median age was 8.0 years, 52% were boys. Of all patients 77% initially presented with hypotension of whom 42% required inotropic support. Treatment in PICU was required in 58% of all patients. Reduced left ventricular ejection fraction was observed in 35% of all patients. Mildly decreased ventricular ejection fraction (

AB - BACKGROUND AND AIM: MIS-C is a hyperinflammatory syndrome caused by Sars-CoV-2 virus. Cardiovascular system impairment is observed up to 100 % of all MIS-C patients with a wide spectrum and severity of symptoms. It is important to identify the course of the disease and its outcome, which could significantly improve public health. METHODS: A single-centre study, prospective cohort study, conducted in the Children’s Clinical University hospital in Latvia from January to December 2021. Patients between the ages of one to seventeen years who met the MIS-C criteria were included in the study. We evaluated blood pressure, left ventricular heart function, size of coronary arteries and hospital course. RESULTS: Thirty-one patients were included who met the MIS-C criteria. The median age was 8.0 years, 52% were boys. Of all patients 77% initially presented with hypotension of whom 42% required inotropic support. Treatment in PICU was required in 58% of all patients. Reduced left ventricular ejection fraction was observed in 35% of all patients. Mildly decreased ventricular ejection fraction (

KW - MIS-C

KW - Hypotension

KW - coronary artery dilation

UR - https://www.aepc2022.org/assets/AEPC-2022-Abstracts-E-Book.pdf

M3 - Abstract

SP - 701

T2 - 55th Annual Meeting of the Association for European Pediatric and Congenital Cardiology (AEPC)

Y2 - 25 May 2022 through 28 May 2022

ER -