SINGLE-CENTRE STUDY: MIS-C IMPACT ON BLOOD PRESSURE, CORONARY ARTERIES AND LEFT VENTRICULAR FUNCTION

Emīls Šmitiņš, Dace Gardovska, Ingūna Lubaua, Inga Lāce, Elīna Ligere, Inta Bergmane, Baiba Matsone-Matsate, Pauls Sīlis, Luīze Auziņa, Ieva Kravale

Research output: Contribution to conferenceAbstractpeer-review

Abstract

BACKGROUND AND AIM: MIS-C is a hyperinflammatory syndrome caused by Sars-CoV-2 virus. Cardiovascular system impairment is observed up to 100 % of all MIS-C patients with a wide spectrum and severity of symptoms. It is important to identify the course of the disease and its outcome, which could significantly improve public health.
METHODS: A single-centre study, prospective cohort study, conducted in the Children’s Clinical University hospital in Latvia from January to December 2021. Patients between the ages of one to seventeen years who met the MIS-C criteria were included in the study. We evaluated blood pressure, left ventricular heart function, size of coronary arteries and hospital course.
RESULTS: Thirty-one patients were included who met the MIS-C criteria. The median age was 8.0 years, 52% were boys. Of all patients 77% initially presented with hypotension of whom 42% required inotropic support. Treatment in PICU was required in 58% of all patients. Reduced left ventricular ejection fraction was observed in 35% of all patients. Mildly decreased ventricular ejection fraction (
Original languageEnglish
Pages701
Number of pages1
Publication statusPublished - 25 May 2022
Event55th Annual Meeting of the Association for European Pediatric and Congenital Cardiology (AEPC) - Geneva, Switzerland
Duration: 25 May 202228 May 2022
Conference number: 55
https://www.aepc.org/aepc-annual-meeting
https://conferencealerts.com/show-event?id=240395

Meeting

Meeting55th Annual Meeting of the Association for European Pediatric and Congenital Cardiology (AEPC)
Abbreviated titleAEPC 2022
Country/TerritorySwitzerland
CityGeneva
Period25/05/2228/05/22
Internet address

Keywords*

  • MIS-C
  • Hypotension
  • coronary artery dilation

Field of Science*

  • 3.2 Clinical medicine

Publication Type*

  • 3.4. Other publications in conference proceedings (including local)

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