TY - JOUR
T1 - Specialist laboratory networks as preparedness and response tool - The emerging viral diseases-expert laboratory network and the chikungunya outbreak, Thailand, 2019
AU - Venturi, Giulietta
AU - Aberle, Stephan W.
AU - Avšič-Županc, Tatjana
AU - Barzon, Luisa
AU - Batejat, Christoph
AU - Burdino, Elisa
AU - Carletti, Fabrizio
AU - Charrel, Rémi
AU - Christova, Iva
AU - Connell, Jeff
AU - Corman, Victor Max
AU - Emmanouil, Mary
AU - Jääskeläinen, Anne J.
AU - Kurolt, Ivan
AU - Lustig, Yaniv
AU - Martinez, Miguel J.
AU - Koopmans, Marion
AU - Nagy, Orsolya
AU - Nguyen, Trung
AU - Papa, Anna
AU - Pérez-Ruiz, Mercedes
AU - Pfeffer, Martin
AU - Protic, Jelena
AU - Reimerink, Johan
AU - Rossini, Giada
AU - Fariñas, María Paz Sánchez Seco
AU - Schmidt-Chanasit, Jonas
AU - Söderholm, Sandra
AU - Sudre, Bertrand
AU - van Esbroeck, Marjan
AU - Reusken, Chantal B.
AU - CHIKV-Working Group
A2 - Argentini, Claudio
A2 - Barbara, Christopher
A2 - Castilletti, Concetta
A2 - Cherpillod, Pascal
A2 - Drosten, Christian
A2 - Edner, Niklas
A2 - Eisermann, Philip
A2 - Engler, Olivier
A2 - Essbauer, Sandra
A2 - Fortuna, Claudia
A2 - Fournier, Guillaume
A2 - Gaibani, Paolo
A2 - Ghisetti, Valeria
A2 - Hewson, Roger
A2 - Karan, Lyudmila
A2 - Korukluoglu, Gulay
A2 - Korva, Miša
A2 - Leparc-Goffart, Isabelle
A2 - Storozenko, Jelena
N1 - Funding Information:
EVD-LabNet is supported by the European Centre for Disease Prevention and Control (ECDC) under the EVD-LabNet Framework contract ECDC/2016/002. We are grateful to Katrin Leitmeyer and Tamas Bakonyi at ECDC for network support.
Publisher Copyright:
© 2020 European Centre for Disease Prevention and Control (ECDC). All rights reserved.
Copyright:
Copyright 2020 Elsevier B.V., All rights reserved.
PY - 2020/4/2
Y1 - 2020/4/2
N2 - We illustrate the potential for specialist laboratory networks to be used as preparedness and response tool through rapid collection and sharing of data. Here, the Emerging Viral Diseases-Expert Laboratory Network (EVD-LabNet) and a laboratory assessment of chikungunya virus (CHIKV) in returning European travellers related to an ongoing outbreak in Thailand was used for this purpose. EVD-LabNet rapidly collected data on laboratory requests, diagnosed CHIKV imported cases and sequences generated, and shared among its members and with the European Centre for Disease Prevention and Control. Data across the network showed an increase in CHIKV imported cases during 1 October 2018-30 April 2019 vs the same period in 2018 (172 vs 50), particularly an increase in cases known to be related to travel to Thailand (72 vs 1). Moreover, EVD-LabNet showed that strains were imported from Thailand that cluster with strains of the ECSA-IOL E1 A226 variant emerging in Pakistan in 2016 and involved in the 2017 outbreaks in Italy. CHIKV diagnostic requests increased by 23.6% between the two periods. The impact of using EVD-LabNet or similar networks as preparedness and response tool could be improved by standardisation of the collection, quality and mining of data in routine laboratory management systems.
AB - We illustrate the potential for specialist laboratory networks to be used as preparedness and response tool through rapid collection and sharing of data. Here, the Emerging Viral Diseases-Expert Laboratory Network (EVD-LabNet) and a laboratory assessment of chikungunya virus (CHIKV) in returning European travellers related to an ongoing outbreak in Thailand was used for this purpose. EVD-LabNet rapidly collected data on laboratory requests, diagnosed CHIKV imported cases and sequences generated, and shared among its members and with the European Centre for Disease Prevention and Control. Data across the network showed an increase in CHIKV imported cases during 1 October 2018-30 April 2019 vs the same period in 2018 (172 vs 50), particularly an increase in cases known to be related to travel to Thailand (72 vs 1). Moreover, EVD-LabNet showed that strains were imported from Thailand that cluster with strains of the ECSA-IOL E1 A226 variant emerging in Pakistan in 2016 and involved in the 2017 outbreaks in Italy. CHIKV diagnostic requests increased by 23.6% between the two periods. The impact of using EVD-LabNet or similar networks as preparedness and response tool could be improved by standardisation of the collection, quality and mining of data in routine laboratory management systems.
UR - http://www.scopus.com/inward/record.url?scp=85083072176&partnerID=8YFLogxK
U2 - 10.2807/1560-7917.ES.2020.25.13.1900438
DO - 10.2807/1560-7917.ES.2020.25.13.1900438
M3 - Article
C2 - 32265004
AN - SCOPUS:85083072176
SN - 1025-496X
VL - 25
SP - 31
EP - 37
JO - Eurosurveillance
JF - Eurosurveillance
IS - 13
ER -
