Spreading of Tissue Spheroids on an Electrospun Polyurethane Matrix

E. V. Koudan; E. A. Bulanova; F. D.A.S. Pereira; V. A. Parfenov; V. A. Kasyanov; U. J. Hesuani; V. A. Mironov

doi:10.1007/s10527-016-9575-5

Spreading of Tissue Spheroids on an Electrospun Polyurethane Matrix

E. V. Koudan, E. A. Bulanova, F. D.A.S. Pereira, V. A. Parfenov, V. A. Kasyanov, U. J. Hesuani, V. A. Mironov

Rīga Stradiņš University

Research output: Contribution to journal › Article › peer-review

4 Citations (Scopus)

Abstract

Tissue spheroids formed from fibroblasts using a micromolded non-adhesive hydrogel were located using a three-dimensional (3D) bioprinter on the surface of a nanofibrous polyurethane matrix produced by electrospinning. It was shown that the tissue spheroids attach to the matrix surface within a few hours and completely flatten after several days, indicating high biocompatibility of the matrix used. Tissue structures formed by the attachment and spreading of tissue spheroids on an electrospun matrix are a new technological platform for biofabrication and 3D bioprinting of tissues and organs.

Original language	English
Pages (from-to)	1-4
Journal	Biomedical Engineering
Volume	50
Issue number	1
DOIs	https://doi.org/10.1007/s10527-016-9575-5
Publication status	Published - 1 May 2016

Field of Science*

2.6 Medical engineering
2.5 Materials engineering

Publication Type*

1.1. Scientific article indexed in Web of Science and/or Scopus database

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10.1007/s10527-016-9575-5

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abstract = "Tissue spheroids formed from fibroblasts using a micromolded non-adhesive hydrogel were located using a three-dimensional (3D) bioprinter on the surface of a nanofibrous polyurethane matrix produced by electrospinning. It was shown that the tissue spheroids attach to the matrix surface within a few hours and completely flatten after several days, indicating high biocompatibility of the matrix used. Tissue structures formed by the attachment and spreading of tissue spheroids on an electrospun matrix are a new technological platform for biofabrication and 3D bioprinting of tissues and organs.",

author = "Koudan, {E. V.} and Bulanova, {E. A.} and Pereira, {F. D.A.S.} and Parfenov, {V. A.} and Kasyanov, {V. A.} and Hesuani, {U. J.} and Mironov, {V. A.}",

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AU - Koudan, E. V.

AU - Bulanova, E. A.

AU - Pereira, F. D.A.S.

AU - Parfenov, V. A.

AU - Kasyanov, V. A.

AU - Hesuani, U. J.

AU - Mironov, V. A.

PY - 2016/5/1

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AB - Tissue spheroids formed from fibroblasts using a micromolded non-adhesive hydrogel were located using a three-dimensional (3D) bioprinter on the surface of a nanofibrous polyurethane matrix produced by electrospinning. It was shown that the tissue spheroids attach to the matrix surface within a few hours and completely flatten after several days, indicating high biocompatibility of the matrix used. Tissue structures formed by the attachment and spreading of tissue spheroids on an electrospun matrix are a new technological platform for biofabrication and 3D bioprinting of tissues and organs.

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DO - 10.1007/s10527-016-9575-5

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JO - Biomedical Engineering

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Spreading of Tissue Spheroids on an Electrospun Polyurethane Matrix

Abstract

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