Study of cardioprotective effect of α-tocopherol and panthenol using an experimental model of ischemized-reperfused isolated heart

A. O. Kumerova, A. P. Skesters, I. Y. Skestere

Research output: Contribution to journalArticlepeer-review

Abstract

Using an experimental ischemia-reperfusion model it is found that combined treatment with α-tocopherol and panthenol markedly increases the content of endogenous antioxidant tocopherol during total ischemia and reperfusion, i.e., it improves the antioxidant state of the postischemized myocardium, thus preventing possible damage caused by stepped-up production of active oxygen forms during reoxygenation.

Original languageEnglish
Pages (from-to)573-575
Number of pages3
JournalBulletin of Experimental Biology and Medicine
Volume117
Issue number6
DOIs
Publication statusPublished - Jun 1994

Keywords

  • antioxidants
  • heart
  • ischemia
  • panthenol
  • perfusion
  • tocopherol

Publication Type

  • 1.1. Scientific article indexed in Web of Science and/or Scopus database

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