Abstract
Background: Thyroid cancer surgical management can vary globally due to differences in healthcare
systems, surgical practices, and resources available. We hypothesized that surgical outcomes in patients
with thyroid cancer would be similar regardless of the care setting if performed by endocrine surgeons.
Methods: Cross-sectional (2019-2022) analysis of thyroidectomy approach and outcome between two
tertiary center in the USA (Center A) and Latvia (Center B) in 770 patients. Demographic,
clinicopathology, extent of thyroidectomy, and outcome were analyzed with multivariable logistic
regression models adjusting for age, sex, and cancer type.
Results: Papillary thyroid cancer was the most common type of thyroid cancer at both centers (~89%),
but the rate of follicular carcinoma was higher in Center A (7% vs. 4%, <0.05) and the rate of medullary
carcinoma was higher in Center B (5% vs. 2%, <0.05). Fine-needle aspiration was utilized more
frequently at Center A (99% vs. 92%, <0.001). There was no significant
difference between centers in the extent of thyroidectomy. The use of intraoperative nerve monitoring
was higher at Center A [(97% vs. 94%, <0.05, (multivariable: OR = 0.48, <0.05)]. The rate of transient
hypoparathyroidism was higher at Center B (3% vs. 1%, <0.05) but there was no significant differences
in the rate of vocal cord dysfunction and length of hospital stay.
Conclusions: This study highlights variations in thyroid cancer surgical management and type of
thyroid cancer between two continents, influenced by resource availability and healthcare systems but
that similar surgical outcomes can be achieved when done by endocrine surgeons.
systems, surgical practices, and resources available. We hypothesized that surgical outcomes in patients
with thyroid cancer would be similar regardless of the care setting if performed by endocrine surgeons.
Methods: Cross-sectional (2019-2022) analysis of thyroidectomy approach and outcome between two
tertiary center in the USA (Center A) and Latvia (Center B) in 770 patients. Demographic,
clinicopathology, extent of thyroidectomy, and outcome were analyzed with multivariable logistic
regression models adjusting for age, sex, and cancer type.
Results: Papillary thyroid cancer was the most common type of thyroid cancer at both centers (~89%),
but the rate of follicular carcinoma was higher in Center A (7% vs. 4%, <0.05) and the rate of medullary
carcinoma was higher in Center B (5% vs. 2%, <0.05). Fine-needle aspiration was utilized more
frequently at Center A (99% vs. 92%, <0.001). There was no significant
difference between centers in the extent of thyroidectomy. The use of intraoperative nerve monitoring
was higher at Center A [(97% vs. 94%, <0.05, (multivariable: OR = 0.48, <0.05)]. The rate of transient
hypoparathyroidism was higher at Center B (3% vs. 1%, <0.05) but there was no significant differences
in the rate of vocal cord dysfunction and length of hospital stay.
Conclusions: This study highlights variations in thyroid cancer surgical management and type of
thyroid cancer between two continents, influenced by resource availability and healthcare systems but
that similar surgical outcomes can be achieved when done by endocrine surgeons.
| Original language | English |
|---|---|
| Pages | 181 |
| Number of pages | 1 |
| Publication status | Published - 2025 |
| Event | 11th Conference of European Society of Endocrine Surgeons - Izmir, Turkey Duration: 22 May 2025 → 24 May 2025 https://eses2025.org/en/ |
Conference
| Conference | 11th Conference of European Society of Endocrine Surgeons |
|---|---|
| Country/Territory | Turkey |
| City | Izmir |
| Period | 22/05/25 → 24/05/25 |
| Internet address |
Field of Science*
- 3.2 Clinical medicine
Publication Type*
- 3.4. Other publications in conference proceedings (including local)
