Synthesis of 4 H-Pyran derivatives under solvent-free and grinding conditions

Rufus Smits; Sergey Belyakov; Aiva Plotniece; Gunars Duburs

doi:10.1080/00397911.2012.716484

Synthesis of 4 H-Pyran derivatives under solvent-free and grinding conditions

Rufus Smits, Sergey Belyakov, Aiva Plotniece, Gunars Duburs

Research output: Contribution to journal › Article › peer-review

12 Citations (Scopus)

Abstract

Based on X-ray diffraction analysis, we have proved that the recently published results for ethyl 6-amino-5-cyano-4-aryl-1,4-dihydropyridine-3- carboxylate synthesis is in fact an environmentally friendly synthesis of 6-amino-5-cyano-4-aryl-4H-pyran derivatives using a multicomponent room-temperature grinding procedure of ethyl acetoacetate, [(2-aryl)methylene] malononitriles, and ammonium acetate.

Original language	English
Pages (from-to)	465-475
Number of pages	11
Journal	Synthetic Communications
Volume	43
Issue number	4
DOIs	https://doi.org/10.1080/00397911.2012.716484
Publication status	Published - 1 Jan 2013
Externally published	Yes

Keywords*

4 H-pyran derivatives
Green synthesis
grinding
multicomponent reactions
solvent-free
X-ray diffraction

Field of Science*

1.4 Chemical sciences

Publication Type*

1.1. Scientific article indexed in Web of Science and/or Scopus database

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10.1080/00397911.2012.716484

Cite this

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title = "Synthesis of 4 H-Pyran derivatives under solvent-free and grinding conditions",

abstract = "Based on X-ray diffraction analysis, we have proved that the recently published results for ethyl 6-amino-5-cyano-4-aryl-1,4-dihydropyridine-3- carboxylate synthesis is in fact an environmentally friendly synthesis of 6-amino-5-cyano-4-aryl-4H-pyran derivatives using a multicomponent room-temperature grinding procedure of ethyl acetoacetate, [(2-aryl)methylene] malononitriles, and ammonium acetate.",

keywords = "4 H-pyran derivatives, Green synthesis, grinding, multicomponent reactions, solvent-free, X-ray diffraction",

author = "Rufus Smits and Sergey Belyakov and Aiva Plotniece and Gunars Duburs",

note = "Funding Information: This work was supported by ESF Project No. 2009/0197/1DP/1.1.1.2.0/09/ APIA/VIAA/014.",

year = "2013",

month = jan,

day = "1",

doi = "10.1080/00397911.2012.716484",

language = "English",

volume = "43",

pages = "465--475",

journal = "Synthetic Communications",

issn = "0039-7911",

publisher = "Taylor and Francis Ltd.",

number = "4",

}

TY - JOUR

T1 - Synthesis of 4 H-Pyran derivatives under solvent-free and grinding conditions

AU - Smits, Rufus

AU - Belyakov, Sergey

AU - Plotniece, Aiva

AU - Duburs, Gunars

N1 - Funding Information: This work was supported by ESF Project No. 2009/0197/1DP/1.1.1.2.0/09/ APIA/VIAA/014.

PY - 2013/1/1

Y1 - 2013/1/1

N2 - Based on X-ray diffraction analysis, we have proved that the recently published results for ethyl 6-amino-5-cyano-4-aryl-1,4-dihydropyridine-3- carboxylate synthesis is in fact an environmentally friendly synthesis of 6-amino-5-cyano-4-aryl-4H-pyran derivatives using a multicomponent room-temperature grinding procedure of ethyl acetoacetate, [(2-aryl)methylene] malononitriles, and ammonium acetate.

AB - Based on X-ray diffraction analysis, we have proved that the recently published results for ethyl 6-amino-5-cyano-4-aryl-1,4-dihydropyridine-3- carboxylate synthesis is in fact an environmentally friendly synthesis of 6-amino-5-cyano-4-aryl-4H-pyran derivatives using a multicomponent room-temperature grinding procedure of ethyl acetoacetate, [(2-aryl)methylene] malononitriles, and ammonium acetate.

KW - 4 H-pyran derivatives

KW - Green synthesis

KW - grinding

KW - multicomponent reactions

KW - solvent-free

KW - X-ray diffraction

UR - http://www.scopus.com/inward/record.url?scp=84869468690&partnerID=8YFLogxK

U2 - 10.1080/00397911.2012.716484

DO - 10.1080/00397911.2012.716484

M3 - Article

AN - SCOPUS:84869468690

SN - 0039-7911

VL - 43

SP - 465

EP - 475

JO - Synthetic Communications

JF - Synthetic Communications

IS - 4

ER -

Synthesis of 4 H-Pyran derivatives under solvent-free and grinding conditions

Abstract

Keywords*

Field of Science*

Publication Type*

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