Temporal trends in COVID-19 outcomes in people with rheumatic diseases in Ireland: data from the COVID-19 Global Rheumatology Alliance registry

Richard Conway (Corresponding Author), Elena Nikiphorou, Christiana A Demetriou, COVID-19 Global Rheumatology Alliance, Julija Zepa (Member of the Working Group), Inita Bulina (Member of the Working Group)

Research output: Contribution to journalArticlepeer-review

5 Citations (Scopus)
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Abstract

OBJECTIVES: Although evidence is accumulating globally, data on outcomes in rheumatic disease and COVID-19 in Ireland are limited. We used data from the COVID-19 Global Rheumatology Alliance (C19-GRA) to describe time-varying COVID-19 outcomes for people with rheumatic disease in Ireland.

METHODS: Data entered into the C19-GRA provider registry from Ireland between 24 March 2020 and 9 July 2021 were analysed. Differences in the likelihood of hospitalization and mortality according to demographic and clinical variables were investigated using Chi-squared test or Fisher's exact test, as appropriate. Trends in odds of hospitalization and mortality over time were investigated using logistic regression with the time period as a categorical variable.

RESULTS: Of 212 cases included, 59.4% were female and median age was 58.0 years (range 13-96). Of the 212 cases, 92 (43%) were hospitalized and 22 (10.4%) died. Increasing age, a diagnosis of gout, ever smoking, glucocorticoid use, having comorbidities and specific comorbidities of cancer, cardiovascular and pulmonary disease were more common in those hospitalized. A diagnosis of inflammatory arthritis, csDMARD and/or b/tsDMARD use were less frequent in those hospitalized. Increasing age, a diagnosis of gout, ever smoking, having comorbidities and specific comorbidities of obesity, cardiovascular and pulmonary disease were more common in those who died. Odds of hospitalization or mortality did not change over time.

CONCLUSION: No temporal trend was observed in either COVID-19-related hospitalization or mortality outcomes for people with rheumatic disease in Ireland.

Original languageEnglish
Pages (from-to)SI151-SI156
JournalRheumatology
Volume61
Issue numberSI2
DOIs
Publication statusPublished - 28 Jun 2022
Externally publishedYes

Keywords*

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • COVID-19/epidemiology
  • Female
  • Gout
  • Humans
  • Ireland/epidemiology
  • Male
  • Middle Aged
  • Registries
  • Rheumatic Diseases/epidemiology
  • Rheumatology
  • SARS-CoV-2
  • Young Adult

Field of Science*

  • 3.2 Clinical medicine

Publication Type*

  • 1.1. Scientific article indexed in Web of Science and/or Scopus database

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