Ternary Phase Diagrams of Naproxen with Soluplus® and Chloroform or Ethyl Acetate

Zoltan Mark Horvath; Katarīna Gurkina; Agris Bērziņš; Roman Viter; Valentyn Mohylyuk

doi:10.13140/RG.2.2.35480.56320

Ternary Phase Diagrams of Naproxen with Soluplus® and Chloroform or Ethyl Acetate

Zoltan Mark Horvath
, Katarīna Gurkina
, Agris Bērziņš
, Roman Viter
, Valentyn Mohylyuk^*

^*Corresponding author for this work

Lead Researcher Group

Research output: Contribution to conference › Poster › peer-review

Original language	English
Number of pages	1
DOIs	https://doi.org/10.13140/RG.2.2.35480.56320
Publication status	Published - 24 Mar 2026
Event	15th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology - Prague Congress Centre, Prague, Czech Republic Duration: 23 Mar 2026 → 26 Mar 2026 Conference number: 15 https://worldmeeting.org/

Meeting

Meeting	15th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology
Abbreviated title	PBP World meeting
Country/Territory	Czech Republic
City	Prague
Period	23/03/26 → 26/03/26
Internet address	https://worldmeeting.org/

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 4 Quality Education
SDG 9 Industry, Innovation, and Infrastructure
SDG 12 Responsible Consumption and Production

Keywords*

Design space
preformulation
formulation
amorphous solid dispersion
solvent method
naproxen
Soluplus
organic solvents
Dynamic Vapor Sorption
differential scanning calorimetry
shake-flask method

Field of Science*

1.4 Chemical sciences
2.4 Chemical engineering
2.5 Materials engineering
3.1 Basic medicine

Publication Type*

3.4. Other publications in conference proceedings (including local)

Access to Document

10.13140/RG.2.2.35480.56320Licence: CC BY

https://www.linkedin.com/feed/update/urn:li:activity:7442866337313366016

3 Poster
2 Meeting abstract
1 Article

Spectroscopic and morphological evaluation of phase behaviour in naproxen-Soluplus solvent-cast films prepared from ethyl acetate and chloroform
Horvath, Z. M., Kačanovs, R., Saršūns, K., Viter, R., Bērziņš, A. & Mohylyuk, V., 26 Aug 2026, 4th International Conference of Contemporary Pharmaceutical Challenges : Advancing Pharmaceutical Science through Interdisciplinary Collaboration . University of Copenhagen, p. 57-58
Research output: Chapter in Book/Report/Conference proceeding › Meeting abstract › Research

Open Access
File
Polymer and solvent candidate selection for the preparation of ASD with naproxen (a bad glass-forming drug)
Horvath, Z. M., Gurkina, K., Kačanovs, R., Bērziņš, A., Viter, R. & Mohylyuk, V., Apr 2026. 1 p.
Research output: Contribution to conference › Poster

Open Access
Elucidation of the mechanism of amorphization and dissolution of bad glass formers as a function of drug-polymer interaction and preparation method: Toward sustainable technologies
Mohylyuk, V., Viter, R. & Bērziņš, A., Apr 2026, 84. Latvijas Universitātes starptautiskā zinātniskā konference = 84th International Scientific Conference of the University of Latvia : Tēžu krājums = Book of Abstracts. Rīga: LU Akadēmiskais apgāds, p. 737-738
Research output: Chapter in Book/Report/Conference proceeding › Meeting abstract › Research › peer-review

Open Access
File

2 Active

Investigation of the composition and preparation process variables on the tabletability and in vitro drug release: focus on the high drug-loaded formulations and poorly soluble drugs
Gurkina, K. (Project leader), Mohylyuk, V. (Supervisor) & Šitovs, A. (Supervisor)
2/02/26 → 2/02/31
Project: Projects not classified elsewhere › PhD project
Elucidation of the mechanism of amorphization and dissolution of bad glass former as a function of drug-polymer interaction and preparation method
Mohylyuk, V. (Project leader), Viter, R. (Partner's coordinator), Žogota, M. (Member of project working group), Horvath, Z. M. (Member of project working group), Kukuls, K. (Member of project working group), Gurkina, K. (Member of project working group), Bērziņš, A. (Member of project working group), Zabolotnii, V. (Member of project working group) & Borovskis, A. (Member of project working group)
Latvian Council of Science
1/01/25 → 31/12/27
Project: Research and development projects financed by the Latvian state budget › Fundamental and Applied Research Projects

3 Poster presentation
2 Participating in a conference, workshop, ...
2 Oral presentation
1 Visiting an external academic institution

Faculty of Pharmaceutical Sciences, Department of Pharmaceutics, Semmelweis University
Horvath, Z. M. (Visiting researcher)
2 Sept 2026
Activity: Visiting an external institution types › Visiting an external academic institution
Spectroscopic and morphological evaluation of phase behaviour in naproxen-Soluplus® solvent-cast films prepared from ethyl acetate and chloroform
Horvath, Z. M. (Speaker), Kačanovs, R. (Co-author), Viter, R. (Co-author), Bērziņš, A. (Co-author) & Mohylyuk, V. (Co-author)
26 Aug 2026 → 28 Aug 2026
Activity: Talk or presentation types › Poster presentation
4th International Conference of Contemporary Pharmaceutical Challenges
Horvath, Z. M. (Participant)
26 Aug 2026 → 28 Aug 2026
Activity: Participating in or organising an event types › Participating in a conference, workshop, ...

Ternary phase diagrams of naproxen with Soluplus® and chloroform or ethyl acetate
Horvath, Z. M., Gurkina, K., Bērziņš, A., Viter, R. & Mohylyuk, V.
9/04/26
1 item of Media coverage
Press/Media

Cite this

@conference{b557c89fe007426e852d2862cadcd26f,

title = "Ternary Phase Diagrams of Naproxen with Soluplus{\textregistered} and Chloroform or Ethyl Acetate",

keywords = "Design space, preformulation, formulation, amorphous solid dispersion, solvent method, naproxen, Soluplus, organic solvents, Dynamic Vapor Sorption, differential scanning calorimetry, shake-flask method",

author = "Horvath, \{Zoltan Mark\} and Katarīna Gurkina and Agris Bērziņ{\v s} and Roman Viter and Valentyn Mohylyuk",

year = "2026",

month = mar,

day = "24",

doi = "10.13140/RG.2.2.35480.56320",

language = "English",

note = "15th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, PBP World meeting ; Conference date: 23-03-2026 Through 26-03-2026",

url = "https://worldmeeting.org/",

}

TY - CONF

T1 - Ternary Phase Diagrams of Naproxen with Soluplus® and Chloroform or Ethyl Acetate

AU - Horvath, Zoltan Mark

AU - Gurkina, Katarīna

AU - Bērziņš, Agris

AU - Viter, Roman

AU - Mohylyuk, Valentyn

N1 - Conference code: 15

PY - 2026/3/24

Y1 - 2026/3/24

KW - Design space

KW - preformulation

KW - formulation

KW - amorphous solid dispersion

KW - solvent method

KW - naproxen

KW - Soluplus

KW - organic solvents

KW - Dynamic Vapor Sorption

KW - differential scanning calorimetry

KW - shake-flask method

U2 - 10.13140/RG.2.2.35480.56320

DO - 10.13140/RG.2.2.35480.56320

M3 - Poster

T2 - 15th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology

Y2 - 23 March 2026 through 26 March 2026

ER -

Ternary Phase Diagrams of Naproxen with Soluplus® and Chloroform or Ethyl Acetate

Meeting

UN SDGs

Keywords*

Field of Science*

Publication Type*

Access to Document

Research output

Projects

Activities

Press/Media

Cite this