The European ME/CFS Biomarker Landscape project: An initiative of the European network EUROMENE

Carmen Scheibenbogen; Helma Freitag; Julià Blanco; Enrica Capelli; Eliana Lacerda; Jerome Authier; Mira Meeus; Jesus Castro Marrero; Zaiga Nora-Krukle; Elisa Oltra; Elin Bolle Strand; Evelina Shikova; Slobodan Sekulic; Modra Murovska

doi:10.1186/s12967-017-1263-z

The European ME/CFS Biomarker Landscape project: An initiative of the European network EUROMENE

Carmen Scheibenbogen, Helma Freitag, Julià Blanco, Enrica Capelli, Eliana Lacerda, Jerome Authier, Mira Meeus, Jesus Castro Marrero, Zaiga Nora-Krukle, Elisa Oltra, Elin Bolle Strand, Evelina Shikova, Slobodan Sekulic, Modra Murovska

Institute of Microbiology and Virology

Research output: Contribution to journal › Review article › peer-review

36 Citations (Scopus)

11 Downloads (Pure)

Abstract

Myalgic encephalomyelitis or chronic fatigue syndrome (ME/CFS) is a common and severe disease with a considerable social and economic impact. So far, the etiology is not known, and neither a diagnostic marker nor licensed treatments are available yet. The EUROMENE network of European researchers and clinicians aims to promote cooperation and advance research on ME/CFS. To improve diagnosis and facilitate the analysis of clinical trials surrogate markers are urgently needed. As a first step for developing such biomarkers for clinical use a database of active biomarker research in Europe was established called the ME/CFS EUROMENE Biomarker Landscape project and the results are presented in this review. Further we suggest strategies to improve biomarker development and encourage researchers to take these into consideration for designing and reporting biomarker studies.

Original language	English
Article number	162
Journal	Journal of Translational Medicine
Volume	15
Issue number	1
DOIs	https://doi.org/10.1186/s12967-017-1263-z
Publication status	Published - 26 Jul 2017

Keywords*

Autoantibodies
Autoimmunity
B cell
Biomarker
Cytokines
Diagnostic
European network
Landscape project
ME/CFS
Viral

Field of Science*

1.6 Biological sciences
3.3 Health sciences

Publication Type*

1.1. Scientific article indexed in Web of Science and/or Scopus database

Access to Document

10.1186/s12967-017-1263-z

The European ME-CFS Biomarker Landscape projectLicence: CC BY

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Scheibenbogen, C., Freitag, H., Blanco, J., Capelli, E., Lacerda, E., Authier, J., Meeus, M., Castro Marrero, J., Nora-Krukle, Z., Oltra, E., Strand, E. B., Shikova, E., Sekulic, S., & Murovska, M. (2017). The European ME/CFS Biomarker Landscape project: An initiative of the European network EUROMENE. Journal of Translational Medicine, 15(1), Article 162. https://doi.org/10.1186/s12967-017-1263-z

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title = "The European ME/CFS Biomarker Landscape project: An initiative of the European network EUROMENE",

abstract = "Myalgic encephalomyelitis or chronic fatigue syndrome (ME/CFS) is a common and severe disease with a considerable social and economic impact. So far, the etiology is not known, and neither a diagnostic marker nor licensed treatments are available yet. The EUROMENE network of European researchers and clinicians aims to promote cooperation and advance research on ME/CFS. To improve diagnosis and facilitate the analysis of clinical trials surrogate markers are urgently needed. As a first step for developing such biomarkers for clinical use a database of active biomarker research in Europe was established called the ME/CFS EUROMENE Biomarker Landscape project and the results are presented in this review. Further we suggest strategies to improve biomarker development and encourage researchers to take these into consideration for designing and reporting biomarker studies.",

keywords = "Autoantibodies, Autoimmunity, B cell, Biomarker, Cytokines, Diagnostic, European network, Landscape project, ME/CFS, Viral",

author = "Carmen Scheibenbogen and Helma Freitag and Juli{\`a} Blanco and Enrica Capelli and Eliana Lacerda and Jerome Authier and Mira Meeus and {Castro Marrero}, Jesus and Zaiga Nora-Krukle and Elisa Oltra and Strand, {Elin Bolle} and Evelina Shikova and Slobodan Sekulic and Modra Murovska",

year = "2017",

month = jul,

day = "26",

doi = "10.1186/s12967-017-1263-z",

language = "English",

volume = "15",

journal = "Journal of Translational Medicine",

issn = "1479-5876",

publisher = "BioMed Central Ltd.",

number = "1",

}

Scheibenbogen, C, Freitag, H, Blanco, J, Capelli, E, Lacerda, E, Authier, J, Meeus, M, Castro Marrero, J, Nora-Krukle, Z, Oltra, E, Strand, EB, Shikova, E, Sekulic, S & Murovska, M 2017, 'The European ME/CFS Biomarker Landscape project: An initiative of the European network EUROMENE', Journal of Translational Medicine, vol. 15, no. 1, 162. https://doi.org/10.1186/s12967-017-1263-z

TY - JOUR

T1 - The European ME/CFS Biomarker Landscape project

T2 - An initiative of the European network EUROMENE

AU - Scheibenbogen, Carmen

AU - Freitag, Helma

AU - Blanco, Julià

AU - Capelli, Enrica

AU - Lacerda, Eliana

AU - Authier, Jerome

AU - Meeus, Mira

AU - Castro Marrero, Jesus

AU - Nora-Krukle, Zaiga

AU - Oltra, Elisa

AU - Strand, Elin Bolle

AU - Shikova, Evelina

AU - Sekulic, Slobodan

AU - Murovska, Modra

PY - 2017/7/26

Y1 - 2017/7/26

N2 - Myalgic encephalomyelitis or chronic fatigue syndrome (ME/CFS) is a common and severe disease with a considerable social and economic impact. So far, the etiology is not known, and neither a diagnostic marker nor licensed treatments are available yet. The EUROMENE network of European researchers and clinicians aims to promote cooperation and advance research on ME/CFS. To improve diagnosis and facilitate the analysis of clinical trials surrogate markers are urgently needed. As a first step for developing such biomarkers for clinical use a database of active biomarker research in Europe was established called the ME/CFS EUROMENE Biomarker Landscape project and the results are presented in this review. Further we suggest strategies to improve biomarker development and encourage researchers to take these into consideration for designing and reporting biomarker studies.

AB - Myalgic encephalomyelitis or chronic fatigue syndrome (ME/CFS) is a common and severe disease with a considerable social and economic impact. So far, the etiology is not known, and neither a diagnostic marker nor licensed treatments are available yet. The EUROMENE network of European researchers and clinicians aims to promote cooperation and advance research on ME/CFS. To improve diagnosis and facilitate the analysis of clinical trials surrogate markers are urgently needed. As a first step for developing such biomarkers for clinical use a database of active biomarker research in Europe was established called the ME/CFS EUROMENE Biomarker Landscape project and the results are presented in this review. Further we suggest strategies to improve biomarker development and encourage researchers to take these into consideration for designing and reporting biomarker studies.

KW - Autoantibodies

KW - Autoimmunity

KW - B cell

KW - Biomarker

KW - Cytokines

KW - Diagnostic

KW - European network

KW - Landscape project

KW - ME/CFS

KW - Viral

UR - http://www.scopus.com/inward/record.url?scp=85026327028&partnerID=8YFLogxK

U2 - 10.1186/s12967-017-1263-z

DO - 10.1186/s12967-017-1263-z

M3 - Review article

C2 - 28747192

AN - SCOPUS:85026327028

SN - 1479-5876

VL - 15

JO - Journal of Translational Medicine

JF - Journal of Translational Medicine

IS - 1

M1 - 162

ER -

The European ME/CFS Biomarker Landscape project: An initiative of the European network EUROMENE

Abstract

Keywords*

Field of Science*

Publication Type*

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