The expression of cytokines and beta -defensin 2,-3,-4 in rabbit bone tissue after hydroxyapatite (HAp), alpha-Tricalcium phosphate (alpha-TCP) and polymethylmethacrylate (PMMA) implantation

J. Vamze; M. Pilmane; A. Skagers

The expression of cytokines and beta -defensin 2,-3,-4 in rabbit bone tissue after hydroxyapatite (HAp), alpha-Tricalcium phosphate (alpha-TCP) and polymethylmethacrylate (PMMA) implantation

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

Abstract

Bone loss induced by inflammation is one of the complications after biomaterial implantation. There is no much data on expression of cytokines and defensins into the bone tissue around the implants in literature. The aim of this work was to investigate the distribution and appearance of interleukin (IL)-1, IL-6, IL-8, IL10 and β – defensin (BD)-2, BD-3, BD-4 after the implantation of different biomaterials. Bone developing zones, signs of bone-implant contact and low expression of pro-inflammatory cytokine IL-1, IL-6 and anti-inflammatory cytokine IL-10 in experimental tissue with pure HAp and unburned HAp implants indicate a potential advantage of this material in terms of its biocompatibility over the other materials used in our study.

Original language	English
Title of host publication	International Conference "Functional Materials and Nanotechnologies" (FM&NT-2012)
Subtitle of host publication	Conference Proceedings
Volume	38
Publication status	Published - 2012
Event	International Conference "Functional Materials and Nanotechnologies" (FM&NT-2012) - Institute of Solid State Physics, University of Latvia, Riga, Latvia Duration: 17 Apr 2012 → 20 Apr 2012 https://www.cfi.lu.lv/lv/notikumi/konferences/cfiorganizetasstarptautiskaskonferencesunpasakumi/gadskarteja-functional-materials-and-nanotechnologies-konference/fmnt-2012/

Publication series

Name	IOP Conference Series: Materials Science and Engineering
Publisher	IOP Publishing Ltd.
ISSN (Print)	1757-8981

Conference

Conference	International Conference "Functional Materials and Nanotechnologies" (FM&NT-2012)
Abbreviated title	FM&NT-2012
Country/Territory	Latvia
City	Riga
Period	17/04/12 → 20/04/12
Other	International Conference on Functional Materials and Nanotechnologies
Internet address	https://www.cfi.lu.lv/lv/notikumi/konferences/cfiorganizetasstarptautiskaskonferencesunpasakumi/gadskarteja-functional-materials-and-nanotechnologies-konference/fmnt-2012/

Field of Science*

1.6 Biological sciences
2.6 Medical engineering

Publication Type*

3.1. Articles or chapters in proceedings/scientific books indexed in Web of Science and/or Scopus database

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Vamze, J., Pilmane, M., & Skagers, A. (2012). The expression of cytokines and beta -defensin 2,-3,-4 in rabbit bone tissue after hydroxyapatite (HAp), alpha-Tricalcium phosphate (alpha-TCP) and polymethylmethacrylate (PMMA) implantation. In International Conference "Functional Materials and Nanotechnologies" (FM&NT-2012): Conference Proceedings (Vol. 38). [012025] (IOP Conference Series: Materials Science and Engineering).

Vamze, J. ; Pilmane, M. ; Skagers, A. / The expression of cytokines and beta -defensin 2,-3,-4 in rabbit bone tissue after hydroxyapatite (HAp), alpha-Tricalcium phosphate (alpha-TCP) and polymethylmethacrylate (PMMA) implantation. International Conference "Functional Materials and Nanotechnologies" (FM&NT-2012): Conference Proceedings. Vol. 38 2012. (IOP Conference Series: Materials Science and Engineering).

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title = "The expression of cytokines and beta -defensin 2,-3,-4 in rabbit bone tissue after hydroxyapatite (HAp), alpha-Tricalcium phosphate (alpha-TCP) and polymethylmethacrylate (PMMA) implantation",

abstract = "Bone loss induced by inflammation is one of the complications after biomaterial implantation. There is no much data on expression of cytokines and defensins into the bone tissue around the implants in literature. The aim of this work was to investigate the distribution and appearance of interleukin (IL)-1, IL-6, IL-8, IL10 and β – defensin (BD)-2, BD-3, BD-4 after the implantation of different biomaterials. Bone developing zones, signs of bone-implant contact and low expression of pro-inflammatory cytokine IL-1, IL-6 and anti-inflammatory cytokine IL-10 in experimental tissue with pure HAp and unburned HAp implants indicate a potential advantage of this material in terms of its biocompatibility over the other materials used in our study.",

author = "J. Vamze and M. Pilmane and A. Skagers",

year = "2012",

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volume = "38",

series = "IOP Conference Series: Materials Science and Engineering",

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booktitle = "International Conference {"}Functional Materials and Nanotechnologies{"} (FM&NT-2012)",

note = "International Conference {"}Functional Materials and Nanotechnologies{"} (FM&NT-2012), FM&NT-2012 ; Conference date: 17-04-2012 Through 20-04-2012",

url = "https://www.cfi.lu.lv/lv/notikumi/konferences/cfiorganizetasstarptautiskaskonferencesunpasakumi/gadskarteja-functional-materials-and-nanotechnologies-konference/fmnt-2012/",

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Vamze, J , Pilmane, M & Skagers, A 2012, The expression of cytokines and beta -defensin 2,-3,-4 in rabbit bone tissue after hydroxyapatite (HAp), alpha-Tricalcium phosphate (alpha-TCP) and polymethylmethacrylate (PMMA) implantation. in International Conference "Functional Materials and Nanotechnologies" (FM&NT-2012): Conference Proceedings. vol. 38, 012025, IOP Conference Series: Materials Science and Engineering, International Conference "Functional Materials and Nanotechnologies" (FM&NT-2012), Riga, Latvia, 17/04/12.

The expression of cytokines and beta -defensin 2,-3,-4 in rabbit bone tissue after hydroxyapatite (HAp), alpha-Tricalcium phosphate (alpha-TCP) and polymethylmethacrylate (PMMA) implantation. / Vamze, J.; Pilmane, M.; Skagers, A.
International Conference "Functional Materials and Nanotechnologies" (FM&NT-2012): Conference Proceedings. Vol. 38 2012. 012025 (IOP Conference Series: Materials Science and Engineering).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

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AU - Skagers, A.

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AB - Bone loss induced by inflammation is one of the complications after biomaterial implantation. There is no much data on expression of cytokines and defensins into the bone tissue around the implants in literature. The aim of this work was to investigate the distribution and appearance of interleukin (IL)-1, IL-6, IL-8, IL10 and β – defensin (BD)-2, BD-3, BD-4 after the implantation of different biomaterials. Bone developing zones, signs of bone-implant contact and low expression of pro-inflammatory cytokine IL-1, IL-6 and anti-inflammatory cytokine IL-10 in experimental tissue with pure HAp and unburned HAp implants indicate a potential advantage of this material in terms of its biocompatibility over the other materials used in our study.

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M3 - Conference contribution

VL - 38

T3 - IOP Conference Series: Materials Science and Engineering

BT - International Conference "Functional Materials and Nanotechnologies" (FM&NT-2012)

T2 - International Conference "Functional Materials and Nanotechnologies" (FM&NT-2012)

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Vamze J , Pilmane M, Skagers A. The expression of cytokines and beta -defensin 2,-3,-4 in rabbit bone tissue after hydroxyapatite (HAp), alpha-Tricalcium phosphate (alpha-TCP) and polymethylmethacrylate (PMMA) implantation. In International Conference "Functional Materials and Nanotechnologies" (FM&NT-2012): Conference Proceedings. Vol. 38. 2012. 012025. (IOP Conference Series: Materials Science and Engineering).

The expression of cytokines and beta -defensin 2,-3,-4 in rabbit bone tissue after hydroxyapatite (HAp), alpha-Tricalcium phosphate (alpha-TCP) and polymethylmethacrylate (PMMA) implantation

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