The outcomes after transfers of embryos with chromosomal mosaicism: a single reproductive medicine center experience at iVF Riga clinic

Baiba Alksere; Ieva Grinfelde; Liene Kornejeva; Aigars Dzalbs; Natalija Vedmedovska; Irina Kovalova; Una Conka; Santa Andersone; Sandra Krasucka; Arita Blumberga; Dace Berzina; Violeta Fodina

doi:10.1080/09513590.2020.1816719

The outcomes after transfers of embryos with chromosomal mosaicism: a single reproductive medicine center experience at iVF Riga clinic

Baiba Alksere, Ieva Grinfelde, Liene Kornejeva, Aigars Dzalbs, Natalija Vedmedovska, Irina Kovalova, Una Conka, Santa Andersone, Sandra Krasucka, Arita Blumberga, Dace Berzina, Violeta Fodina (Corresponding Author)

Rīga Stradiņš University

Research output: Contribution to journal › Article › peer-review

2 Citations (Scopus)

94 Downloads (Pure)

Abstract

Aim: The aim of this study is to summarize the outcomes of transfers of mosaic embryos, which were classified according to guidelines and in strong collaboration of reproductologists, clinical geneticists and patients approved as suitable for transfer. Material and Methods: Retrospective data were collected from 70 patients from a private IVF center to whom embryos with mosaic changes in chromosomal material were transferred from 2015 to 2019. Results and Conclusion: Implantation outcomes and continuing pregnancies showed slight differences, when compared to fully normal embryos. Artifacts have to be differentiated from undeniable aberrations, and correct interpretation of results must be done with following patient counselling and prenatal testing if necessary.

Original language	English
Pages (from-to)	53-57
Number of pages	5
Journal	Gynecological Endocrinology
Volume	36
Issue number	S1
DOIs	https://doi.org/10.1080/09513590.2020.1816719
Publication status	Published - 2020

Keywords*

IVF
mosaic embryos
PGT-A
pregnancy

Field of Science*

3.2 Clinical medicine

Publication Type*

1.1. Scientific article indexed in Web of Science and/or Scopus database

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1080/09513590.2020.1816719

The outcomes after transfers of embryos with chromosomal mosaicismFinal published version, 1.27 MBLicence: CC BY

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Alksere, B., Grinfelde, I., Kornejeva, L., Dzalbs, A., Vedmedovska, N., Kovalova, I., Conka, U., Andersone, S., Krasucka, S., Blumberga, A., Berzina, D., & Fodina, V. (2020). The outcomes after transfers of embryos with chromosomal mosaicism: a single reproductive medicine center experience at iVF Riga clinic. Gynecological Endocrinology, 36(S1), 53-57. https://doi.org/10.1080/09513590.2020.1816719

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title = "The outcomes after transfers of embryos with chromosomal mosaicism: a single reproductive medicine center experience at iVF Riga clinic",

abstract = "Aim: The aim of this study is to summarize the outcomes of transfers of mosaic embryos, which were classified according to guidelines and in strong collaboration of reproductologists, clinical geneticists and patients approved as suitable for transfer. Material and Methods: Retrospective data were collected from 70 patients from a private IVF center to whom embryos with mosaic changes in chromosomal material were transferred from 2015 to 2019. Results and Conclusion: Implantation outcomes and continuing pregnancies showed slight differences, when compared to fully normal embryos. Artifacts have to be differentiated from undeniable aberrations, and correct interpretation of results must be done with following patient counselling and prenatal testing if necessary.",

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year = "2020",

doi = "10.1080/09513590.2020.1816719",

language = "English",

volume = "36",

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Alksere, B, Grinfelde, I, Kornejeva, L, Dzalbs, A, Vedmedovska, N, Kovalova, I, Conka, U, Andersone, S, Krasucka, S, Blumberga, A, Berzina, D & Fodina, V 2020, 'The outcomes after transfers of embryos with chromosomal mosaicism: a single reproductive medicine center experience at iVF Riga clinic', Gynecological Endocrinology, vol. 36, no. S1, pp. 53-57. https://doi.org/10.1080/09513590.2020.1816719

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T1 - The outcomes after transfers of embryos with chromosomal mosaicism

T2 - a single reproductive medicine center experience at iVF Riga clinic

AU - Alksere, Baiba

AU - Grinfelde, Ieva

AU - Kornejeva, Liene

AU - Dzalbs, Aigars

AU - Vedmedovska, Natalija

AU - Kovalova, Irina

AU - Conka, Una

AU - Andersone, Santa

AU - Krasucka, Sandra

AU - Blumberga, Arita

AU - Berzina, Dace

AU - Fodina, Violeta

N1 - Publisher Copyright: © 2020 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group on behalf of the UR MED GRUPP (LLC). Copyright: Copyright 2020 Elsevier B.V., All rights reserved.

PY - 2020

Y1 - 2020

N2 - Aim: The aim of this study is to summarize the outcomes of transfers of mosaic embryos, which were classified according to guidelines and in strong collaboration of reproductologists, clinical geneticists and patients approved as suitable for transfer. Material and Methods: Retrospective data were collected from 70 patients from a private IVF center to whom embryos with mosaic changes in chromosomal material were transferred from 2015 to 2019. Results and Conclusion: Implantation outcomes and continuing pregnancies showed slight differences, when compared to fully normal embryos. Artifacts have to be differentiated from undeniable aberrations, and correct interpretation of results must be done with following patient counselling and prenatal testing if necessary.

AB - Aim: The aim of this study is to summarize the outcomes of transfers of mosaic embryos, which were classified according to guidelines and in strong collaboration of reproductologists, clinical geneticists and patients approved as suitable for transfer. Material and Methods: Retrospective data were collected from 70 patients from a private IVF center to whom embryos with mosaic changes in chromosomal material were transferred from 2015 to 2019. Results and Conclusion: Implantation outcomes and continuing pregnancies showed slight differences, when compared to fully normal embryos. Artifacts have to be differentiated from undeniable aberrations, and correct interpretation of results must be done with following patient counselling and prenatal testing if necessary.

KW - IVF

KW - mosaic embryos

KW - PGT-A

KW - pregnancy

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SN - 0951-3590

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The outcomes after transfers of embryos with chromosomal mosaicism: a single reproductive medicine center experience at iVF Riga clinic

Abstract

Keywords*

Field of Science*

Publication Type*

UN SDGs

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