Projects per year
Abstract
The growing market of herbal medicines, the increase in international trade in Latvia, and the lack of adequate analytical methods have raised the question of the potential use of herbal fingerprinting methods. In this study, high-performance liquid chromatography (HPLC) and thin layer chromatography (TLC) methods were developed for obtaining chromatographic fingerprints of four taxonomically and evolutionary different medicinal plants ( Hibiscus sabdariffa L., Calendula officinalis L., Matricaria recutita L., Achillea millefolium L.). Retention time shifting, principal component analysis (PCA), hierarchical cluster analysis (HCA), and orthogonal projections to latent structures (OPLS) analysis were used to improve and analyze the obtained fingerprints. HPLC data detection at 270 nm was determined superior to 360 nm for the distinction of medicinal plants and used data alignment method significantly increased similarity between samples. Analyzed medicinal plant extracts formed separate, compact clusters in PCA, and the results of HCA correlated with the evolutionary relationships of the analyzed medicinal plants. Herbal fingerprinting using chromatographic analysis coupled with multivariate analysis has a great potential for the identification of medicinal plants as well as for the distinction of Latvian native medicinal plants.
Original language | English |
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Article number | 2555 |
Journal | Molecules |
Volume | 27 |
Issue number | 8 |
DOIs | |
Publication status | Published - 1 Apr 2022 |
Field of Science*
- 3.1 Basic medicine
Publication Type*
- 1.1. Scientific article indexed in Web of Science and/or Scopus database
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Dive into the research topics of 'The Potential Use of Herbal Fingerprints by Means of HPLC and TLC for Characterization and Identification of Herbal Extracts and the Distinction of Latvian Native Medicinal Plants'. Together they form a unique fingerprint.Projects
- 1 Active
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BBCE: Baltic Biomaterials Centre of Excellence, Phase II
Ločs, J. (Project leader), Bandere, D. (Leading expert), Logviss, K. (Work package leader), Brangule, A. (Partner's coordinator), Krūmiņa, J. (Work package leader), Bārzdiņa, A. (Expert (PhD student)) & Prudņikova, D. P. (Assistant (student))
1/01/20 → 31/12/26
Project: EU Programmes › Horizon 2020