Abstract
The gold standard in the treatment of hypertrophic obstructive cardiomyopathy is transaortic surgical
myectomy, a technique with a proven 60-year track record, which eliminates obstruction and improves
symptoms and, therefore, functional capacity and with established cost-effectiveness. Newer pharmacological agents such as myosin inhibitors are now being tested in clinical practice. A surgical alternative
has recently been introduced, transapical beating-heart septal myectomy. This approach has the same
goals as transaortic myectomy and offers additional advantages such as its minimally invasive nature, as no cardiopulmonary bypass and cardiac arrest are needed, together with a real-time assessment of resection with intraoperative transesophageal echocardiography. Time is needed, however, surgical treatment of patients with an appropriate indication for septal myectomy will benefit from this newly introduced procedure.
myectomy, a technique with a proven 60-year track record, which eliminates obstruction and improves
symptoms and, therefore, functional capacity and with established cost-effectiveness. Newer pharmacological agents such as myosin inhibitors are now being tested in clinical practice. A surgical alternative
has recently been introduced, transapical beating-heart septal myectomy. This approach has the same
goals as transaortic myectomy and offers additional advantages such as its minimally invasive nature, as no cardiopulmonary bypass and cardiac arrest are needed, together with a real-time assessment of resection with intraoperative transesophageal echocardiography. Time is needed, however, surgical treatment of patients with an appropriate indication for septal myectomy will benefit from this newly introduced procedure.
Original language | English |
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Number of pages | 4 |
Journal | Cirugia Cardiovascular |
DOIs | |
Publication status | E-pub ahead of print - 9 May 2025 |
Keywords*
- Hypertrophic obstructive cardiomyopathy
- Septal reduction therapy
- Transaortic septal myectomy
- Transapical beating heart myectomy
Field of Science*
- 3.2 Clinical medicine
Publication Type*
- 1.4. Reviewed scientific article published in Latvia or abroad in a scientific journal with an editorial board (including university editions)