Transapical beating-heart septal myectomy, a game changer in the treatment of obstructive hypertrophic cardiomyopathy: The Wei operation: La miectomía septal transapical a corazón latiente, un cambio de paradigma en el tratamiento de la cardiomiopatía hipertrófica obstructiva: la operación de Wei

Carlos Alberto Mestres Lucio (Corresponding Author), Pēteris Stradiņš, Gvido Vārpiņš, Cristina Ibáñez, Eduard Quintana

Research output: Contribution to journalArticlepeer-review

Abstract

The gold standard in the treatment of hypertrophic obstructive cardiomyopathy is transaortic surgical
myectomy, a technique with a proven 60-year track record, which eliminates obstruction and improves
symptoms and, therefore, functional capacity and with established cost-effectiveness. Newer pharmacological agents such as myosin inhibitors are now being tested in clinical practice. A surgical alternative
has recently been introduced, transapical beating-heart septal myectomy. This approach has the same
goals as transaortic myectomy and offers additional advantages such as its minimally invasive nature, as no cardiopulmonary bypass and cardiac arrest are needed, together with a real-time assessment of resection with intraoperative transesophageal echocardiography. Time is needed, however, surgical treatment of patients with an appropriate indication for septal myectomy will benefit from this newly introduced procedure.
Original languageEnglish
Number of pages4
JournalCirugia Cardiovascular
DOIs
Publication statusE-pub ahead of print - 9 May 2025

Keywords*

  • Hypertrophic obstructive cardiomyopathy
  • Septal reduction therapy
  • Transaortic septal myectomy
  • Transapical beating heart myectomy

Field of Science*

  • 3.2 Clinical medicine

Publication Type*

  • 1.4. Reviewed scientific article published in Latvia or abroad in a scientific journal with an editorial board (including university editions)

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