Transferrin variants as markers of migrations and admixture between populations in the Baltic Sea region

L. Beckman, C. Sikström, A. V. Mikelsaar, A. Krumina, D. Ambrasiene, V. Kučinskas, G. Beckman

Research output: Contribution to journalArticlepeer-review

12 Citations (Scopus)

Abstract

Transferrin (TF) types were examined by isoelectric focusing in an attempt to elucidate migrations and admixture between populations in the Baltic Sea region. A highly significant heterogeneity between populations was found with respect to TF(*)C subtypes as well as the rare TF variants B2, BO-1 and DCHI. With the exception for Estonia, increased frequencies of the TF(*)C3 allele were observed east of the Baltic Sea. The island of Gotland in the middle of the Baltic Sea also showed a high TF(*)C3 frequency indicating an eastern influence. The TF(*)DCHI allele, a marker of eastern (Finno-Ugric) influence, was found in Finland and Estonia and on the island of Gotland, but not in mainland Sweden and in the Baltic peoples (Latvians and Lithuanians). These results indicate the presence of a Finno-Ugric, most likely Estonian or Livonian, genetic influence in the Gotland population.

Original languageEnglish
Pages (from-to)185-191
Number of pages7
JournalHuman Heredity
Volume48
Issue number4
DOIs
Publication statusPublished - Jul 1998
Externally publishedYes

Keywords

  • Admixture
  • Baltic populations
  • Migration
  • Transferrin

Field of Science

  • 3.1 Basic medicine
  • 3.2 Clinical medicine

Publication Type

  • 1.1. Scientific article indexed in Web of Science and/or Scopus database

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