Twin-screw melt granulation with PEG 8000: Effect of binder particle size and processing temperature on the granule and tablet properties

Search results

• 2025

  Sorbitol as a melt binder in twin-screw melt granulation for effervescent tablets preparation

  Horvath, Z. M., Kukuls, K., Frolova, A. J., Žogota, M., Buczkowska, E. M., Pētersone, L. & Mohylyuk, V. (Corresponding Author), Jun 2025. 1 p.

  Research output: Contribution to conference › Poster

  Open Access

  File

  3 Downloads (Pure)

• Effervescent Tablet Preparation by Twin-Screw Melt Granulation with Sorbitol as a Melt Binder

  Horvath, Z. M., Kukuls, K., Frolova, A. J., Žogota, M., Buczkowska, E. M., Pētersone, L. & Mohylyuk, V. (Corresponding Author), 21 May 2025, In: Pharmaceutics. 17, 5, 15 p., 676.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Sorbitol 100%
  • Twins 100%
  • Tensile Strength 100%
  • Sodium Bicarbonate 100%
  • Polyol 100%

  1 Citation (Scopus)

  9 Downloads (Pure)

• Effect of Magnesium Stearate Lubrication on the Tableting of Spray-dried Grades of Mannitol and Fluid-Bed Granulated Grade of Isomalt

  Mohylyuk, V. (Corresponding Author), Kukuls, K., Frolova, A. J., Horvath, Z. M., Buczkowska, E. M. & Pētersone, L., 24 Mar 2025, p. M034 .

  Research output: Contribution to conference › Poster

  Open Access

  File

  6 Downloads (Pure)

• 2024

  Dwell Time on Tableting: Dwell Time According to Force versus Geometric Dwell Time

  Mohylyuk, V. (Corresponding Author), Sept 2024, In: Pharmaceutical Development and Technology. 29, 7, p. 719-726

  Research output: Contribution to journal › Article › peer-review

  • Tablet 100%
  • Tableting 100%
  • Calcium Phosphate 33%
  • Microcrystalline Cellulose 33%
  • Cellulose Phosphate 33%

  2 Citations (Scopus)

• The Increase in the Plasticity of Microcrystalline Cellulose Spheres’ When Loaded with a Plasticizer

  Paulausks, A., Kolisnyk, T. & Mohylyuk, V. (Corresponding Author), 16 Jul 2024, In: Pharmaceutics. 16, 7, 945.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Plasticizer 100%
  • Microcrystalline Cellulose 100%
  • Feasibility Study 100%
  • Differential Scanning Calorimetry 100%
  • Microcrystalline 100%

  7 Citations (Scopus)

  6 Downloads (Pure)

• Modification of mechanical properties of microcrystalline cellulose (MCC) by loading it with a plasticizer

  Paulausks, A., Kolisnyk, T. & Mohylyuk, V., 8 Jul 2024. 2 p.

  Research output: Contribution to conference › Abstract › peer-review

• Mechanical properties of tablets: direct compression vs. twin-screw melt granulation with PEG 8000

  Mohylyuk, V. (Corresponding Author), Horvath, Z. M., Kukuls, K., Lauberte, L. & Paulausks, A., 21 May 2024. 1 p.

  Research output: Contribution to conference › Poster

  Open Access

• Twin-Screw Melt Granulation with PEG 8000: Effect of binder particle size and processing temperature on the granule and tablet properties

  Horvath, Z. M., Lauberte, L. & Mohylyuk, V., 21 Mar 2024. 1 p.

  Research output: Contribution to conference › Poster › peer-review

  Open Access

  File

  21 Downloads (Pure)

• Compaction and Structural-Mechanical Properties of Tablets as a Function of Volume Ratios of Excipients

  Mohylyuk, V. (Corresponding Author), Paulausks, A., Radzins, O. & Lauberte, L., 19 Mar 2024. 1 p.

  Research output: Contribution to conference › Poster › peer-review

  Open Access

  File

  20 Downloads (Pure)

• The Effect of Microcrystalline Cellulose–CaHPO4 Mixtures in Different Volume Ratios on the Compaction and Structural–Mechanical Properties of Tablets

  Mohylyuk, V. (Corresponding Author), Paulausks, A., Radzins, O. & Lauberte, L., 5 Mar 2024, In: Pharmaceutics. 16, 3, 362.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Tablet 100%
  • Microcrystalline Cellulose 100%
  • Microcrystallinity 100%
  • Calcium Phosphate 100%
  • dies 75%

  7 Citations (Scopus)

  9 Downloads (Pure)