Using powder rheology to assess the effect of microcrystalline cellulose sphere size on performance in a wurster fluid-bed coater

Tim Freeman; Rajeev Dattani; Valentyn Mohylyuk; Gavin P. Andrews; Ioanna Danai Styliari

Using powder rheology to assess the effect of microcrystalline cellulose sphere size on performance in a wurster fluid-bed coater

Tim Freeman (Corresponding Author), Rajeev Dattani, Valentyn Mohylyuk, Gavin P. Andrews, Ioanna Danai Styliari

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

Abstract

Repeatable and differentiating data via powder rheology measurements. In fluid bed coaters, powders are required to flow under low stress conditions, in confined states, and as a stream of fluidised particles. All these regimes can be intuitively linked with the test conditions applied to measure different flow properties. Beyond being more differentiating, there are stronger grounds to expect robust correlations between the flow energy and coater performance.

Original language	English
Title of host publication	2020 AIChE Annual Meeting
Subtitle of host publication	Proceedings
Publisher	American Institute of Chemical Engineers
ISBN (Electronic)	9780816911141
Publication status	Published - 2020
Externally published	Yes
Event	2020 AIChE Annual Meeting - Online Duration: 16 Nov 2020 → 20 Nov 2020 https://www.aiche.org/conferences/aiche-annual-meeting/2020

Publication series

Name	AIChE Annual Meeting, Conference Proceedings
Volume	2020-November

Conference

Conference	2020 AIChE Annual Meeting
Period	16/11/20 → 20/11/20
Internet address	https://www.aiche.org/conferences/aiche-annual-meeting/2020

Field of Science*

1.4 Chemical sciences
2.4 Chemical engineering

Publication Type*

3.1. Articles or chapters in proceedings/scientific books indexed in Web of Science and/or Scopus database

Cite this

Freeman, T., Dattani, R., Mohylyuk, V., Andrews, G. P., & Styliari, I. D. (2020). Using powder rheology to assess the effect of microcrystalline cellulose sphere size on performance in a wurster fluid-bed coater. In 2020 AIChE Annual Meeting: Proceedings Article 168750 (AIChE Annual Meeting, Conference Proceedings; Vol. 2020-November). American Institute of Chemical Engineers.

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title = "Using powder rheology to assess the effect of microcrystalline cellulose sphere size on performance in a wurster fluid-bed coater",

abstract = "Repeatable and differentiating data via powder rheology measurements. In fluid bed coaters, powders are required to flow under low stress conditions, in confined states, and as a stream of fluidised particles. All these regimes can be intuitively linked with the test conditions applied to measure different flow properties. Beyond being more differentiating, there are stronger grounds to expect robust correlations between the flow energy and coater performance.",

author = "Tim Freeman and Rajeev Dattani and Valentyn Mohylyuk and Andrews, {Gavin P.} and Styliari, {Ioanna Danai}",

note = "Publisher Copyright: {\textcopyright} 2020 Freeman Technology; 2020 AIChE Annual Meeting ; Conference date: 16-11-2020 Through 20-11-2020",

year = "2020",

language = "English",

series = "AIChE Annual Meeting, Conference Proceedings",

publisher = "American Institute of Chemical Engineers",

booktitle = "2020 AIChE Annual Meeting",

address = "United States",

url = "https://www.aiche.org/conferences/aiche-annual-meeting/2020",

}

Freeman, T, Dattani, R, Mohylyuk, V, Andrews, GP & Styliari, ID 2020, Using powder rheology to assess the effect of microcrystalline cellulose sphere size on performance in a wurster fluid-bed coater. in 2020 AIChE Annual Meeting: Proceedings., 168750, AIChE Annual Meeting, Conference Proceedings, vol. 2020-November, American Institute of Chemical Engineers, 2020 AIChE Annual Meeting, 16/11/20.

Using powder rheology to assess the effect of microcrystalline cellulose sphere size on performance in a wurster fluid-bed coater. / Freeman, Tim (Corresponding Author); Dattani, Rajeev; Mohylyuk, Valentyn et al.
2020 AIChE Annual Meeting: Proceedings. American Institute of Chemical Engineers, 2020. 168750 (AIChE Annual Meeting, Conference Proceedings; Vol. 2020-November).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

TY - GEN

T1 - Using powder rheology to assess the effect of microcrystalline cellulose sphere size on performance in a wurster fluid-bed coater

AU - Freeman, Tim

AU - Dattani, Rajeev

AU - Mohylyuk, Valentyn

AU - Andrews, Gavin P.

AU - Styliari, Ioanna Danai

PY - 2020

Y1 - 2020

N2 - Repeatable and differentiating data via powder rheology measurements. In fluid bed coaters, powders are required to flow under low stress conditions, in confined states, and as a stream of fluidised particles. All these regimes can be intuitively linked with the test conditions applied to measure different flow properties. Beyond being more differentiating, there are stronger grounds to expect robust correlations between the flow energy and coater performance.

AB - Repeatable and differentiating data via powder rheology measurements. In fluid bed coaters, powders are required to flow under low stress conditions, in confined states, and as a stream of fluidised particles. All these regimes can be intuitively linked with the test conditions applied to measure different flow properties. Beyond being more differentiating, there are stronger grounds to expect robust correlations between the flow energy and coater performance.

UR - http://www.scopus.com/inward/record.url?scp=85106203063&partnerID=8YFLogxK

UR - https://www.aiche.org/academy/conferences/aiche-annual-meeting/2020/proceeding

M3 - Conference contribution

AN - SCOPUS:85106203063

T3 - AIChE Annual Meeting, Conference Proceedings

BT - 2020 AIChE Annual Meeting

PB - American Institute of Chemical Engineers

T2 - 2020 AIChE Annual Meeting

Y2 - 16 November 2020 through 20 November 2020

ER -

Using powder rheology to assess the effect of microcrystalline cellulose sphere size on performance in a wurster fluid-bed coater

Abstract

Publication series

Conference

Field of Science*

Publication Type*

Other files and links

Fingerprint

Journal of Drug Delivery Science and Technology (Journal)

Cite this

Using powder rheology to assess the effect of microcrystalline cellulose sphere size on performance in a wurster fluid-bed coater

Abstract

Publication series

Conference

Field of Science*

Publication Type*

Other files and links

Fingerprint

Activities

Journal of Drug Delivery Science and Technology (Journal)

Cite this