VARIATION OF SERUM VITAMIN B12 LEVEL IN THE BLOOD FROM PATIENTS OF DIFFERENT AGE AMONG THE LATVIAN POPULATION

Didzis Gavars; Dmitry Perminov; Eriks Tauckels; Ilze Lindenberga; Agnese Miķelsone; Agris Auce

doi:10.2478/prolas-2024-0020

VARIATION OF SERUM VITAMIN B12 LEVEL IN THE BLOOD FROM PATIENTS OF DIFFERENT AGE AMONG THE LATVIAN POPULATION

Didzis Gavars, Dmitry Perminov, Eriks Tauckels, Ilze Lindenberga, Agnese Miķelsone, Agris Auce (Corresponding Author)

Research output: Contribution to journal › Article › peer-review

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Abstract

The reference intervals and median values of serum vitamin B12 level in blood from patients among the Latvian population were established for different age groups with a two-year step using data for a large number of patients, accumulated in E. Gulbis Laboratory in Latvia. The data represents the general population of Latvia. An indirect in silico method, developed in E. Gulbis laboratory for determination of serum vitamin B12 blood level reference intervals, was used. Strong elevation of serum vitamin B12 blood level was observed in children who were between 2 and 10 years old. The paper discusses the serum vitamin B12 values for children and a different serum vitamin B12 reference interval for young children is suggested.

Original language	English
Pages (from-to)	133-140
Number of pages	8
Journal	Proceedings of the Latvian Academy of Sciences, Section B: Natural, Exact, and Applied Sciences
Volume	78
Issue number	2
DOIs	https://doi.org/10.2478/prolas-2024-0020
Publication status	Published - 1 Apr 2024
Externally published	Yes

Keywords*

B12 vitamin
children
general population
in silico analysis
large patient data
Latvia
reference interval

Field of Science*

3.1 Basic medicine
3.3 Health sciences

Publication Type*

1.1. Scientific article indexed in Web of Science and/or Scopus database

Access to Document

10.2478/prolas-2024-0020Licence: CC BY

Variation-of-Serum-Vitamin-B12-Level-in-the-Blood-from-Patients-of-Different-Age-Among-the-Latvian-PopulationFinal published version, 889 KBLicence: CC BY

Cite this

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title = "VARIATION OF SERUM VITAMIN B12 LEVEL IN THE BLOOD FROM PATIENTS OF DIFFERENT AGE AMONG THE LATVIAN POPULATION",

abstract = "The reference intervals and median values of serum vitamin B12 level in blood from patients among the Latvian population were established for different age groups with a two-year step using data for a large number of patients, accumulated in E. Gulbis Laboratory in Latvia. The data represents the general population of Latvia. An indirect in silico method, developed in E. Gulbis laboratory for determination of serum vitamin B12 blood level reference intervals, was used. Strong elevation of serum vitamin B12 blood level was observed in children who were between 2 and 10 years old. The paper discusses the serum vitamin B12 values for children and a different serum vitamin B12 reference interval for young children is suggested.",

keywords = "B12 vitamin, children, general population, in silico analysis, large patient data, Latvia, reference interval",

author = "Didzis Gavars and Dmitry Perminov and Eriks Tauckels and Ilze Lindenberga and Agnese Miķelsone and Agris Auce",

note = "Publisher Copyright: {\textcopyright} The Authors This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).",

year = "2024",

month = apr,

day = "1",

doi = "10.2478/prolas-2024-0020",

language = "English",

volume = "78",

pages = "133--140",

journal = "Proceedings of the Latvian Academy of Sciences, Section B: Natural, Exact, and Applied Sciences",

issn = "1407-009X",

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VARIATION OF SERUM VITAMIN B12 LEVEL IN THE BLOOD FROM PATIENTS OF DIFFERENT AGE AMONG THE LATVIAN POPULATION. / Gavars, Didzis; Perminov, Dmitry; Tauckels, Eriks et al.
In: Proceedings of the Latvian Academy of Sciences, Section B: Natural, Exact, and Applied Sciences, Vol. 78, No. 2, 01.04.2024, p. 133-140.

Research output: Contribution to journal › Article › peer-review

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AU - Gavars, Didzis

AU - Perminov, Dmitry

AU - Tauckels, Eriks

AU - Lindenberga, Ilze

AU - Miķelsone, Agnese

AU - Auce, Agris

N1 - Publisher Copyright: © The Authors This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

PY - 2024/4/1

Y1 - 2024/4/1

N2 - The reference intervals and median values of serum vitamin B12 level in blood from patients among the Latvian population were established for different age groups with a two-year step using data for a large number of patients, accumulated in E. Gulbis Laboratory in Latvia. The data represents the general population of Latvia. An indirect in silico method, developed in E. Gulbis laboratory for determination of serum vitamin B12 blood level reference intervals, was used. Strong elevation of serum vitamin B12 blood level was observed in children who were between 2 and 10 years old. The paper discusses the serum vitamin B12 values for children and a different serum vitamin B12 reference interval for young children is suggested.

AB - The reference intervals and median values of serum vitamin B12 level in blood from patients among the Latvian population were established for different age groups with a two-year step using data for a large number of patients, accumulated in E. Gulbis Laboratory in Latvia. The data represents the general population of Latvia. An indirect in silico method, developed in E. Gulbis laboratory for determination of serum vitamin B12 blood level reference intervals, was used. Strong elevation of serum vitamin B12 blood level was observed in children who were between 2 and 10 years old. The paper discusses the serum vitamin B12 values for children and a different serum vitamin B12 reference interval for young children is suggested.

KW - B12 vitamin

KW - children

KW - general population

KW - in silico analysis

KW - large patient data

KW - Latvia

KW - reference interval

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VARIATION OF SERUM VITAMIN B12 LEVEL IN THE BLOOD FROM PATIENTS OF DIFFERENT AGE AMONG THE LATVIAN POPULATION

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