Zlokachestvennaia limfoma s "volosatymi" limfotsitami v krovi i splenomegalieǐ--novyǐ variant limfoproliferativnogo zabolevaniia..

L. L. Lavorkovskiǐ; A. G. Merson; N. M. Gipsh; N. M. Karminskaia; S. V. Nikul'shin; L. N. Guseva; L. I. Lavorkovskiǐ

Zlokachestvennaia limfoma s "volosatymi" limfotsitami v krovi i splenomegalieǐ--novyǐ variant limfoproliferativnogo zabolevaniia..

Translated title of the contribution: Malignant lymphoma with "hairy" lymphocytes in the blood and splenomegaly--a new variant of lymphoproliferative diseases

L. L. Lavorkovskiǐ (Corresponding Author), A. G. Merson, N. M. Gipsh, N. M. Karminskaia, S. V. Nikul'shin, L. N. Guseva, L. I. Lavorkovskiǐ

Research output: Contribution to journal › Article › peer-review

Abstract

A total of 5 patients with a clinicohematological picture resembling hairy-cell leukemia (HCL) have been described. However, the morphological features of leukemic lymphocytes, the absence of acid phosphatase in them, the nodular character of the bone marrow lesion combined with an unusual phenotype have permitted the authors to distinguish these cases as a separate variant of B-cell malignant lymphoma. Paraprotein (M-class) was detected in the blood of two of the patients. A conclusion has been made that the combination of splenomegaly with hairy lymphocytes in the blood is characteristic of not only HCL, but it can be also observed in different variants of malignant lymphoma.

Translated title of the contribution	Malignant lymphoma with "hairy" lymphocytes in the blood and splenomegaly--a new variant of lymphoproliferative diseases
Original language	Russian
Pages (from-to)	12-16
Number of pages	5
Journal	Gematologiya i Transfusiologiya
Volume	35
Issue number	6
Publication status	Published - Jun 1990
Externally published	Yes

Field of Science*

3.2 Clinical medicine

Publication Type*

1.1. Scientific article indexed in Web of Science and/or Scopus database

Cite this

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title = "Zlokachestvennaia limfoma s {"}volosatymi{"} limfotsitami v krovi i splenomegalieǐ--novyǐ variant limfoproliferativnogo zabolevaniia..",

abstract = "A total of 5 patients with a clinicohematological picture resembling hairy-cell leukemia (HCL) have been described. However, the morphological features of leukemic lymphocytes, the absence of acid phosphatase in them, the nodular character of the bone marrow lesion combined with an unusual phenotype have permitted the authors to distinguish these cases as a separate variant of B-cell malignant lymphoma. Paraprotein (M-class) was detected in the blood of two of the patients. A conclusion has been made that the combination of splenomegaly with hairy lymphocytes in the blood is characteristic of not only HCL, but it can be also observed in different variants of malignant lymphoma.",

author = "Lavorkovskiǐ, {L. L.} and Merson, {A. G.} and Gipsh, {N. M.} and Karminskaia, {N. M.} and Nikul'shin, {S. V.} and Guseva, {L. N.} and Lavorkovskiǐ, {L. I.}",

year = "1990",

month = jun,

language = "Russian",

volume = "35",

pages = "12--16",

journal = "Gematologiya i Transfusiologiya",

issn = "0234-5730",

publisher = "Izdatel'stvo Meditsina",

number = "6",

}

TY - JOUR

T1 - Zlokachestvennaia limfoma s "volosatymi" limfotsitami v krovi i splenomegalieǐ--novyǐ variant limfoproliferativnogo zabolevaniia..

AU - Lavorkovskiǐ, L. L.

AU - Merson, A. G.

AU - Gipsh, N. M.

AU - Karminskaia, N. M.

AU - Nikul'shin, S. V.

AU - Guseva, L. N.

AU - Lavorkovskiǐ, L. I.

PY - 1990/6

Y1 - 1990/6

N2 - A total of 5 patients with a clinicohematological picture resembling hairy-cell leukemia (HCL) have been described. However, the morphological features of leukemic lymphocytes, the absence of acid phosphatase in them, the nodular character of the bone marrow lesion combined with an unusual phenotype have permitted the authors to distinguish these cases as a separate variant of B-cell malignant lymphoma. Paraprotein (M-class) was detected in the blood of two of the patients. A conclusion has been made that the combination of splenomegaly with hairy lymphocytes in the blood is characteristic of not only HCL, but it can be also observed in different variants of malignant lymphoma.

AB - A total of 5 patients with a clinicohematological picture resembling hairy-cell leukemia (HCL) have been described. However, the morphological features of leukemic lymphocytes, the absence of acid phosphatase in them, the nodular character of the bone marrow lesion combined with an unusual phenotype have permitted the authors to distinguish these cases as a separate variant of B-cell malignant lymphoma. Paraprotein (M-class) was detected in the blood of two of the patients. A conclusion has been made that the combination of splenomegaly with hairy lymphocytes in the blood is characteristic of not only HCL, but it can be also observed in different variants of malignant lymphoma.

UR - http://www.scopus.com/inward/record.url?scp=0025441371&partnerID=8YFLogxK

M3 - Article

C2 - 2394362

AN - SCOPUS:0025441371

SN - 0234-5730

VL - 35

SP - 12

EP - 16

JO - Gematologiya i Transfusiologiya

JF - Gematologiya i Transfusiologiya

IS - 6

ER -

Zlokachestvennaia limfoma s "volosatymi" limfotsitami v krovi i splenomegalieǐ--novyǐ variant limfoproliferativnogo zabolevaniia..

Abstract

Field of Science*

Publication Type*

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